Real‐world use of inhaled treprostinil for lung disease‐pulmonary hypertension: A protocol for patient evaluation and prescribing

Abstract Inhaled treprostinil was approved recently for interstitial lung disease‐pulmonary hypertension; however, efficacy in “real‐world” populations is not known. We designed a protocol and report our experience evaluating 10 patients referred for therapy. Misdiagnosis at presentation was common;...

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Main Authors: Shelsey W. Johnson, Lauren Finlay, Stephen C. Mathai, Ronald H. Goldstein, Bradley A. Maron
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Pulmonary Circulation
Subjects:
Online Access:https://doi.org/10.1002/pul2.12126
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author Shelsey W. Johnson
Lauren Finlay
Stephen C. Mathai
Ronald H. Goldstein
Bradley A. Maron
author_facet Shelsey W. Johnson
Lauren Finlay
Stephen C. Mathai
Ronald H. Goldstein
Bradley A. Maron
author_sort Shelsey W. Johnson
collection DOAJ
description Abstract Inhaled treprostinil was approved recently for interstitial lung disease‐pulmonary hypertension; however, efficacy in “real‐world” populations is not known. We designed a protocol and report our experience evaluating 10 patients referred for therapy. Misdiagnosis at presentation was common; ultimately, three patients (30%) were prescribed drug. This protocol offers an opportunity to standardize longitudinal assessment of inhaled treprostinil in clinical practice.
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spelling doaj.art-5707562ec5764b82986cb9cdf09a7e952022-12-22T02:56:58ZengWileyPulmonary Circulation2045-89402022-07-01123n/an/a10.1002/pul2.12126Real‐world use of inhaled treprostinil for lung disease‐pulmonary hypertension: A protocol for patient evaluation and prescribingShelsey W. Johnson0Lauren Finlay1Stephen C. Mathai2Ronald H. Goldstein3Bradley A. Maron4Department of Pulmonary, Allergy, Sleep, and Critical Care Medicine, VA Boston Healthcare System Boston Massachusetts USADepartment of Pharmacy VA Boston Healthcare System Boston Massachusetts USADepartment of Pulmonary and Critical Care Medicine Johns Hopkins University, and Johns Hopkins School of Medicine Baltimore Maryland USADepartment of Pulmonary, Allergy, Sleep, and Critical Care Medicine, VA Boston Healthcare System Boston Massachusetts USADepartment of Pulmonary, Allergy, Sleep, and Critical Care Medicine, VA Boston Healthcare System Boston Massachusetts USAAbstract Inhaled treprostinil was approved recently for interstitial lung disease‐pulmonary hypertension; however, efficacy in “real‐world” populations is not known. We designed a protocol and report our experience evaluating 10 patients referred for therapy. Misdiagnosis at presentation was common; ultimately, three patients (30%) were prescribed drug. This protocol offers an opportunity to standardize longitudinal assessment of inhaled treprostinil in clinical practice.https://doi.org/10.1002/pul2.12126Group 3 pulmonary hypertensioninhaled treprostinilinterstitial lung diseasepulmonary hypertension
spellingShingle Shelsey W. Johnson
Lauren Finlay
Stephen C. Mathai
Ronald H. Goldstein
Bradley A. Maron
Real‐world use of inhaled treprostinil for lung disease‐pulmonary hypertension: A protocol for patient evaluation and prescribing
Pulmonary Circulation
Group 3 pulmonary hypertension
inhaled treprostinil
interstitial lung disease
pulmonary hypertension
title Real‐world use of inhaled treprostinil for lung disease‐pulmonary hypertension: A protocol for patient evaluation and prescribing
title_full Real‐world use of inhaled treprostinil for lung disease‐pulmonary hypertension: A protocol for patient evaluation and prescribing
title_fullStr Real‐world use of inhaled treprostinil for lung disease‐pulmonary hypertension: A protocol for patient evaluation and prescribing
title_full_unstemmed Real‐world use of inhaled treprostinil for lung disease‐pulmonary hypertension: A protocol for patient evaluation and prescribing
title_short Real‐world use of inhaled treprostinil for lung disease‐pulmonary hypertension: A protocol for patient evaluation and prescribing
title_sort real world use of inhaled treprostinil for lung disease pulmonary hypertension a protocol for patient evaluation and prescribing
topic Group 3 pulmonary hypertension
inhaled treprostinil
interstitial lung disease
pulmonary hypertension
url https://doi.org/10.1002/pul2.12126
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