Lessons and Challenges for Measles Control from Unexpected Large Outbreak, Malawi
Despite high reported coverage for routine and supplementary immunization, in 2010 in Malawi, a large measles outbreak occurred that comprised 134,000 cases and 304 deaths. Although the highest attack rates were for young children (2.3%, 7.6%, and 4.5% for children <6, 6–8, and 9–11 months, respe...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2013-02-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/19/2/12-0301_article |
| _version_ | 1818536712498839552 |
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| author | Andrea Minetti Matthew Kagoli Agnes Katsulukuta Helena Huerga Amber Featherstone Hazel Chiotcha Delphine Noel Cameron Bopp Laurent Sury Renzo Fricke Marta Iscla Northan Hurtado Tanya Ducomble Sarala Nicholas Storn Kabuluzi Rebecca F. Grais Francisco J. Luquero |
| author_facet | Andrea Minetti Matthew Kagoli Agnes Katsulukuta Helena Huerga Amber Featherstone Hazel Chiotcha Delphine Noel Cameron Bopp Laurent Sury Renzo Fricke Marta Iscla Northan Hurtado Tanya Ducomble Sarala Nicholas Storn Kabuluzi Rebecca F. Grais Francisco J. Luquero |
| author_sort | Andrea Minetti |
| collection | DOAJ |
| description | Despite high reported coverage for routine and supplementary immunization, in 2010 in Malawi, a large measles outbreak occurred that comprised 134,000 cases and 304 deaths. Although the highest attack rates were for young children (2.3%, 7.6%, and 4.5% for children <6, 6–8, and 9–11 months, respectively), persons >15 years of age were highly affected (1.0% and 0.4% for persons 15–19 and >19 years, respectively; 28% of all cases). A survey in 8 districts showed routine coverage of 95.0% for children 12–23 months; 57.9% for children 9–11 months; and 60.7% for children covered during the last supplementary immunization activities in 2008. Vaccine effectiveness was 83.9% for 1 dose and 90.5% for 2 doses. A continuous accumulation of susceptible persons during the past decade probably accounts for this outbreak. Countries en route to measles elimination, such as Malawi, should improve outbreak preparedness. Timeliness and the population chosen are crucial elements for reactive campaigns. |
| first_indexed | 2024-12-11T18:41:28Z |
| format | Article |
| id | doaj.art-5709d0f62f3f4fc296314acea8cf0128 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-11T18:41:28Z |
| publishDate | 2013-02-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-5709d0f62f3f4fc296314acea8cf01282022-12-22T00:54:36ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592013-02-0119220220910.3201/eid1902.120301Lessons and Challenges for Measles Control from Unexpected Large Outbreak, MalawiAndrea MinettiMatthew KagoliAgnes KatsulukutaHelena HuergaAmber FeatherstoneHazel ChiotchaDelphine NoelCameron BoppLaurent SuryRenzo FrickeMarta IsclaNorthan HurtadoTanya DucombleSarala NicholasStorn KabuluziRebecca F. GraisFrancisco J. LuqueroDespite high reported coverage for routine and supplementary immunization, in 2010 in Malawi, a large measles outbreak occurred that comprised 134,000 cases and 304 deaths. Although the highest attack rates were for young children (2.3%, 7.6%, and 4.5% for children <6, 6–8, and 9–11 months, respectively), persons >15 years of age were highly affected (1.0% and 0.4% for persons 15–19 and >19 years, respectively; 28% of all cases). A survey in 8 districts showed routine coverage of 95.0% for children 12–23 months; 57.9% for children 9–11 months; and 60.7% for children covered during the last supplementary immunization activities in 2008. Vaccine effectiveness was 83.9% for 1 dose and 90.5% for 2 doses. A continuous accumulation of susceptible persons during the past decade probably accounts for this outbreak. Countries en route to measles elimination, such as Malawi, should improve outbreak preparedness. Timeliness and the population chosen are crucial elements for reactive campaigns.https://wwwnc.cdc.gov/eid/article/19/2/12-0301_articlemeaslesdisease outbreaksvirusesvaccinationExpanded Program on ImmunizationMalawi |
| spellingShingle | Andrea Minetti Matthew Kagoli Agnes Katsulukuta Helena Huerga Amber Featherstone Hazel Chiotcha Delphine Noel Cameron Bopp Laurent Sury Renzo Fricke Marta Iscla Northan Hurtado Tanya Ducomble Sarala Nicholas Storn Kabuluzi Rebecca F. Grais Francisco J. Luquero Lessons and Challenges for Measles Control from Unexpected Large Outbreak, Malawi Emerging Infectious Diseases measles disease outbreaks viruses vaccination Expanded Program on Immunization Malawi |
| title | Lessons and Challenges for Measles Control from Unexpected Large Outbreak, Malawi |
| title_full | Lessons and Challenges for Measles Control from Unexpected Large Outbreak, Malawi |
| title_fullStr | Lessons and Challenges for Measles Control from Unexpected Large Outbreak, Malawi |
| title_full_unstemmed | Lessons and Challenges for Measles Control from Unexpected Large Outbreak, Malawi |
| title_short | Lessons and Challenges for Measles Control from Unexpected Large Outbreak, Malawi |
| title_sort | lessons and challenges for measles control from unexpected large outbreak malawi |
| topic | measles disease outbreaks viruses vaccination Expanded Program on Immunization Malawi |
| url | https://wwwnc.cdc.gov/eid/article/19/2/12-0301_article |
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