Ebola Virus ─ A Global Threat

Ebola virus is a filamentous, enveloped, non-segmented, single-stranded, negative-sense RNA virus. It belongs to the Filoviridae and was first recognized near the Ebola River valley in Zaire in 1976. Since then most of the outbreaks have occurred to both human and nonhuman primates in sub-Saharan Af...

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Main Authors: Mejbah Uddin Ahmed, Sushmita Roy
Format: Article
Language:English
Published: Enam Medical College, Dhaka 2015-01-01
Series:Journal of Enam Medical College
Subjects:
Online Access:http://www.banglajol.info/index.php/JEMC/article/view/21497
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author Mejbah Uddin Ahmed
Sushmita Roy
author_facet Mejbah Uddin Ahmed
Sushmita Roy
author_sort Mejbah Uddin Ahmed
collection DOAJ
description Ebola virus is a filamentous, enveloped, non-segmented, single-stranded, negative-sense RNA virus. It belongs to the Filoviridae and was first recognized near the Ebola River valley in Zaire in 1976. Since then most of the outbreaks have occurred to both human and nonhuman primates in sub-Saharan Africa. Ebola virus causes highly fatal hemorrhagic fever in human and nonhuman primates. In addition to hemorrhagic fever, it could be used as a bioterrorism agent. Although its natural reservoir is yet to be proven, current data suggest that fruit bats are the possibility. Infection has also been documented through the handling of infected chimpanzees, gorillas, monkeys, forest antelope and porcupines. Human infection is caused through close contact with the blood, secretion, organ or other body fluids of infected animal. Human-to-human transmission is also possible. Ebola virus infections are characterized by immune suppression and a systemic inflammatory response that causes impairment of the vascular, coagulation, and immune systems, leading to multiorgan failure and shock. The virus constitutes an important public health threat in Africa and also worldwide as no effective treatment or vaccine is available till now
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spelling doaj.art-5709e89ba1ac4dbf94107983f09b4c8d2022-12-21T18:11:53ZengEnam Medical College, DhakaJournal of Enam Medical College2227-66882304-93162015-01-0151445110.3329/jemc.v5i1.21497Ebola Virus ─ A Global ThreatMejbah Uddin Ahmed0Sushmita Roy1Associate Professor, Department of Microbiology, Enam Medical College, Savar, Dhaka, Bangladesh Assistant Professor, Department of Microbiology, Enam Medical College, Savar, Dhaka, Bangladesh Ebola virus is a filamentous, enveloped, non-segmented, single-stranded, negative-sense RNA virus. It belongs to the Filoviridae and was first recognized near the Ebola River valley in Zaire in 1976. Since then most of the outbreaks have occurred to both human and nonhuman primates in sub-Saharan Africa. Ebola virus causes highly fatal hemorrhagic fever in human and nonhuman primates. In addition to hemorrhagic fever, it could be used as a bioterrorism agent. Although its natural reservoir is yet to be proven, current data suggest that fruit bats are the possibility. Infection has also been documented through the handling of infected chimpanzees, gorillas, monkeys, forest antelope and porcupines. Human infection is caused through close contact with the blood, secretion, organ or other body fluids of infected animal. Human-to-human transmission is also possible. Ebola virus infections are characterized by immune suppression and a systemic inflammatory response that causes impairment of the vascular, coagulation, and immune systems, leading to multiorgan failure and shock. The virus constitutes an important public health threat in Africa and also worldwide as no effective treatment or vaccine is available till nowhttp://www.banglajol.info/index.php/JEMC/article/view/21497Ebola virus; Hemorrhagic fever; Fruit bats
spellingShingle Mejbah Uddin Ahmed
Sushmita Roy
Ebola Virus ─ A Global Threat
Journal of Enam Medical College
Ebola virus; Hemorrhagic fever; Fruit bats
title Ebola Virus ─ A Global Threat
title_full Ebola Virus ─ A Global Threat
title_fullStr Ebola Virus ─ A Global Threat
title_full_unstemmed Ebola Virus ─ A Global Threat
title_short Ebola Virus ─ A Global Threat
title_sort ebola virus ─ a global threat
topic Ebola virus; Hemorrhagic fever; Fruit bats
url http://www.banglajol.info/index.php/JEMC/article/view/21497
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