| Summary: | The wear of acrylic denture teeth is a serious problem that can change the vertical dimensions of dentures. This study evaluates the effect of adding salinized nano ZrO<sub>2</sub> particles on the microstructure, hardness, and wear resistance of acrylic denture teeth. Heat polymerizing polymethyl methacrylate resin was mixed with salinized ZrO<sub>2</sub> at concentrations of 5 wt.% and 10 wt.%. Acrylic resin specimens without filler addition were used as a control group. SEM/EDS analyses were performed and the Vickers’ hardness was evaluated. Two-body wear testing was performed using a chewing simulator with a human enamel antagonist. After subjecting the samples to 37,500 cycles, both height loss and weight loss were used to evaluate the wear behavior. The microstructural investigation of the reinforced-denture teeth indicates sound nanocomposite preparation using the applied regime without porosity or macro defects. The addition of zirconium oxide nanofillers to PMMA at both 5% and 10% increased the microhardness, with values of up to 49.7 HV. The wear mechanism in the acrylic base material without nanoparticle addition was found to be fatigue wear; a high density of microcracks were found. The addition of 5 wt.% ZrO<sub>2</sub> improved the wear resistance. Increasing the nanoparticles to 10 wt.% ZrO<sub>2</sub> further improved the wear resistance, with no microcracks found.
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