Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer

Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer

Aptamers are valuable tools that provide great potential to develop cost-effective diagnostics and therapies in the biomedical field. Here, we report a novel DNA aptamer that folds into an unconventional G-quadruplex structure able to recognize and enter specifically into human Burkitt's lympho...

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Bibliographic Details
Main Authors: Felipe Opazo, Laura Eiden, Line Hansen, Falk Rohrbach, Jesper Wengel, Jørgen Kjems, Günter Mayer
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Aptamers
G-cuadruplex
Burkitt´s lymphoma
RAMOS
bi-paratopic
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116300361

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