Association of Hearing Acuity and Cognitive Function Among a Low-Income Elderly Population in Rural China: A Population-Based Cross-Sectional Study
Hearing loss is a modifiable risk factor for dementia and cognitive decline. However, the association between cognition and hearing acuity at different frequencies is unknown. We aimed to assess the relationships between hearing acuity at different frequencies with global cognitive function and five...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-08-01
|
| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2021.704871/full |
| _version_ | 1819081542038716416 |
|---|---|
| author | Yi Xu Yan Li Dandan Guo Xin Zhang Huiying Guo Hui Cao Xin Li Jing Zhang Jun Tu Jun Tu Jun Tu Jinghua Wang Jinghua Wang Jinghua Wang Xianjia Ning Xianjia Ning Xianjia Ning Dong Yang |
| author_facet | Yi Xu Yan Li Dandan Guo Xin Zhang Huiying Guo Hui Cao Xin Li Jing Zhang Jun Tu Jun Tu Jun Tu Jinghua Wang Jinghua Wang Jinghua Wang Xianjia Ning Xianjia Ning Xianjia Ning Dong Yang |
| author_sort | Yi Xu |
| collection | DOAJ |
| description | Hearing loss is a modifiable risk factor for dementia and cognitive decline. However, the association between cognition and hearing acuity at different frequencies is unknown. We aimed to assess the relationships between hearing acuity at different frequencies with global cognitive function and five domains of cognition among a low-income elderly population in northern rural China. A population-based cross-sectional study was conducted to collect basic information from elderly residents aged 60 years and older in rural areas of Tianjin, China from April 2012 to November 2013. Pure tone averages (PTAs) at different frequencies in the ear with better hearing and Mini-Mental State Examination (MMSE) scores were measured, and the relationships between these variables were assessed. A total of 737 residents aged 60 years or more were enrolled in this study, and the prevalence of hearing impairment was 60.7%. After adjusting for sex, age, education, income, smoking, drinking, systolic blood pressure (SBP), total cholesterol (TC), and low-density lipoprotein cholesterol level (LDL-C), MMSE score and immediate recall score were negatively associated with overall PTA (OPTA) at four frequencies (0.5, 1, 2, and 4 kHz), PTA at low frequencies (LPTA; 0.5, 1, and 2 kHz), and PTA at high frequencies (HPTA; 3, 4, and 8 kHz) in the ear with better hearing. Moreover, orientation score was negatively associated with OPTA and LPTA, and the attention and calculation scores were negatively associated with OPTA and HPTA. Each 10-dB increase in OPTA was associated with a MMSE score decrease of 0.464. Each 10-dB increase in LPTA or HPTA was associated with a MMSE score decrease of 0.441 (95% CI: −0.795, −0.086) and 0.351 (95% CI: −0.592, −0.110), respectively. The present study demonstrated significant but weak relationships between OPTA, LPTA, and HPTA with global cognitive function, as defined using MMSE scores; these relationships were independent of age, education, lifestyle factors, and laboratory test values. These results indicated that hearing was associated with cognitive decline among older individuals, who should be screened routinely to identify risk for cognitive decline. |
| first_indexed | 2024-12-21T20:02:26Z |
| format | Article |
| id | doaj.art-571acaaf147e42a28a27da8443346715 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-21T20:02:26Z |
| publishDate | 2021-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-571acaaf147e42a28a27da84433467152022-12-21T18:51:56ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2021-08-011510.3389/fnins.2021.704871704871Association of Hearing Acuity and Cognitive Function Among a Low-Income Elderly Population in Rural China: A Population-Based Cross-Sectional StudyYi Xu0Yan Li1Dandan Guo2Xin Zhang3Huiying Guo4Hui Cao5Xin Li6Jing Zhang7Jun Tu8Jun Tu9Jun Tu10Jinghua Wang11Jinghua Wang12Jinghua Wang13Xianjia Ning14Xianjia Ning15Xianjia Ning16Dong Yang17Department of Otorhinolaryngology, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of Anesthesiology, Tianjin Jizhou People’s Hospital, Tianjin, ChinaDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of Otorhinolaryngology, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of Otorhinolaryngology, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of Otorhinolaryngology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, ChinaDepartment of Otorhinolaryngology, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, ChinaLaboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, ChinaKey Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in Central Nervous System, Tianjin Neurological Institute, Ministry of Education and Tianjin City, Tianjin, ChinaDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, ChinaLaboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, ChinaKey Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in Central Nervous System, Tianjin Neurological Institute, Ministry of Education and Tianjin City, Tianjin, ChinaDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, ChinaLaboratory of Epidemiology, Tianjin Neurological Institute, Tianjin, ChinaKey Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in Central Nervous System, Tianjin Neurological Institute, Ministry of Education and Tianjin City, Tianjin, ChinaDepartment of Otorhinolaryngology, Tianjin Medical University General Hospital, Tianjin, ChinaHearing loss is a modifiable risk factor for dementia and cognitive decline. However, the association between cognition and hearing acuity at different frequencies is unknown. We aimed to assess the relationships between hearing acuity at different frequencies with global cognitive function and five domains of cognition among a low-income elderly population in northern rural China. A population-based cross-sectional study was conducted to collect basic information from elderly residents aged 60 years and older in rural areas of Tianjin, China from April 2012 to November 2013. Pure tone averages (PTAs) at different frequencies in the ear with better hearing and Mini-Mental State Examination (MMSE) scores were measured, and the relationships between these variables were assessed. A total of 737 residents aged 60 years or more were enrolled in this study, and the prevalence of hearing impairment was 60.7%. After adjusting for sex, age, education, income, smoking, drinking, systolic blood pressure (SBP), total cholesterol (TC), and low-density lipoprotein cholesterol level (LDL-C), MMSE score and immediate recall score were negatively associated with overall PTA (OPTA) at four frequencies (0.5, 1, 2, and 4 kHz), PTA at low frequencies (LPTA; 0.5, 1, and 2 kHz), and PTA at high frequencies (HPTA; 3, 4, and 8 kHz) in the ear with better hearing. Moreover, orientation score was negatively associated with OPTA and LPTA, and the attention and calculation scores were negatively associated with OPTA and HPTA. Each 10-dB increase in OPTA was associated with a MMSE score decrease of 0.464. Each 10-dB increase in LPTA or HPTA was associated with a MMSE score decrease of 0.441 (95% CI: −0.795, −0.086) and 0.351 (95% CI: −0.592, −0.110), respectively. The present study demonstrated significant but weak relationships between OPTA, LPTA, and HPTA with global cognitive function, as defined using MMSE scores; these relationships were independent of age, education, lifestyle factors, and laboratory test values. These results indicated that hearing was associated with cognitive decline among older individuals, who should be screened routinely to identify risk for cognitive decline.https://www.frontiersin.org/articles/10.3389/fnins.2021.704871/fullcognitive functionhearing losspure tone averagelow-frequency pure tone averageaging |
| spellingShingle | Yi Xu Yan Li Dandan Guo Xin Zhang Huiying Guo Hui Cao Xin Li Jing Zhang Jun Tu Jun Tu Jun Tu Jinghua Wang Jinghua Wang Jinghua Wang Xianjia Ning Xianjia Ning Xianjia Ning Dong Yang Association of Hearing Acuity and Cognitive Function Among a Low-Income Elderly Population in Rural China: A Population-Based Cross-Sectional Study Frontiers in Neuroscience cognitive function hearing loss pure tone average low-frequency pure tone average aging |
| title | Association of Hearing Acuity and Cognitive Function Among a Low-Income Elderly Population in Rural China: A Population-Based Cross-Sectional Study |
| title_full | Association of Hearing Acuity and Cognitive Function Among a Low-Income Elderly Population in Rural China: A Population-Based Cross-Sectional Study |
| title_fullStr | Association of Hearing Acuity and Cognitive Function Among a Low-Income Elderly Population in Rural China: A Population-Based Cross-Sectional Study |
| title_full_unstemmed | Association of Hearing Acuity and Cognitive Function Among a Low-Income Elderly Population in Rural China: A Population-Based Cross-Sectional Study |
| title_short | Association of Hearing Acuity and Cognitive Function Among a Low-Income Elderly Population in Rural China: A Population-Based Cross-Sectional Study |
| title_sort | association of hearing acuity and cognitive function among a low income elderly population in rural china a population based cross sectional study |
| topic | cognitive function hearing loss pure tone average low-frequency pure tone average aging |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2021.704871/full |
| work_keys_str_mv | AT yixu associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT yanli associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT dandanguo associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT xinzhang associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT huiyingguo associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT huicao associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT xinli associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT jingzhang associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT juntu associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT juntu associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT juntu associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT jinghuawang associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT jinghuawang associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT jinghuawang associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT xianjianing associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT xianjianing associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT xianjianing associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy AT dongyang associationofhearingacuityandcognitivefunctionamongalowincomeelderlypopulationinruralchinaapopulationbasedcrosssectionalstudy |