Exploration of KCNJ5 Somatic Mutation and CYP11B1/CYP11B2 Staining in Multiple Nodules in Primary Aldosteronism

Exploration of KCNJ5 Somatic Mutation and CYP11B1/CYP11B2 Staining in Multiple Nodules in Primary Aldosteronism

ObjectiveUnilateral primary aldosteronism (PA) includes aldosterone-producing adenoma (APA), unilateral adrenal hyperplasia, and unilateral multiple nodules. The correlation of multiple nodules, especially genotypic and pathological characteristics, remains unknown. KCNJ5 mutation accounts for 60–80...

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Bibliographic Details
Main Authors: Jing Xie, Cui Zhang, Xuefeng Wang, Yiran Jiang, Luming Wu, Lei Ye, Xuan Wang, Wen Xie, Haimin Xu, Weiqing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Medicine
Subjects:
KCNJ5
CYP11B2
CYP11B1
primary aldosteronism
unilateral multiple nodules
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.823065/full

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