miR-7 Regulates GLP-1-Mediated Insulin Release by Targeting β-Arrestin 1

miR-7 Regulates GLP-1-Mediated Insulin Release by Targeting β-Arrestin 1

Glucagon-like peptide-1 (GLP-1) has been shown to potentiate glucose-stimulated insulin secretion binding GLP-1 receptor on pancreatic β cells. β-arrestin 1 (βARR1) is known to regulate the desensitization of GLP-1 receptor. Mounting evidence indicates that microRNAs (miRNAs, miRs) are fundamental i...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Alessandro Matarese, Jessica Gambardella, Angela Lombardi, Xujun Wang, Gaetano Santulli
Format:	Article
Sprog:	English
Udgivet:	MDPI AG 2020-07-01
Serier:	Cells
Fag:	β-arrestin 1 cAMP diabetes epigenetics glucose-stimulated insulin secretion (GSIS) miRNA-7
Online adgang:	https://www.mdpi.com/2073-4409/9/7/1621

Lignende værker

Comparative Effects of GLP-1 and GLP-2 on Beta-Cell Function, Glucose Homeostasis and Appetite Regulation
af: Asif Ali, et al.
Udgivet: (2024-11-01)

Olive Oil Lipophenols Induce Insulin Secretion in 832/13 β-Cell Models
af: Maria Cristina Caroleo, et al.
Udgivet: (2021-07-01)

Hypertonicity during a rapid rise in D-glucose mediates first-phase insulin secretion
af: Varun Kamat, et al.
Udgivet: (2024-06-01)

Preliminary Study on the Protective Effects and Molecular Mechanism of Procyanidins against PFOS-Induced Glucose-Stimulated Insulin Secretion Impairment in INS-1 Cells
af: Hai-Ming Xu, et al.
Udgivet: (2023-02-01)

MiR-184 regulates insulin secretion through repression of Slc25a22
af: Sumiyo Morita, et al.
Udgivet: (2013-09-01)

Divergent acute versus prolonged pharmacological GLP-1R responses in adult β cell-specific β-arrestin 2 knockout mice
af: Bitsi, Stavroula, et al.
Udgivet: (2023)

miR-145a-5p/SIK1/cAMP-dependent alteration of synaptic structural plasticity drives cognitive impairment induced by coke oven emissions
af: Zhaoxu Wu, et al.
Udgivet: (2024-06-01)

RGS4-Deficiency Alters Intracellular Calcium and PKA-Mediated Control of Insulin Secretion in Glucose-Stimulated Beta Islets
af: Guillaume Bastin, et al.
Udgivet: (2021-08-01)

Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling
af: Gemma Navarro, et al.
Udgivet: (2024-10-01)

Receptor-Arrestin Interactions: The GPCR Perspective
af: Mohammad Seyedabadi, et al.
Udgivet: (2021-02-01)

Notch signalling pathway as an oncogenic factor involved in cancer development
af: Marlena Brzozowa-Zasada, et al.
Udgivet: (2016-09-01)

Biological Evaluation of a Mitochondrial Phosphoenolpyruvate Carboxykinase Inhibitor
af: Sergio Rodríguez-Arévalo, et al.
Udgivet: (2019-09-01)

Mammalian D-Cysteine controls insulin secretion in the pancreas
af: Robin Roychaudhuri, et al.
Udgivet: (2024-12-01)

Modeling the Amino Acid Effect on Glucagon Secretion from Pancreatic Alpha Cells
af: Jan Zmazek, et al.
Udgivet: (2022-04-01)

Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase
af: Nguyen-Tu, Marie-Sophie, et al.
Udgivet: (2022)

Structural features of arrestin-mediated GPCR signaling
af: Wenqin Xie, et al.
Udgivet: (2024-12-01)

The Atypical Chemerin Receptor GPR1 Displays Different Modes of Interaction with β-Arrestins in Humans and Mice with Important Consequences on Subcellular Localization and Trafficking
af: Gaetan-Nagim Degroot, et al.
Udgivet: (2022-03-01)

miR-98 Regulates TMPRSS2 Expression in Human Endothelial Cells: Key Implications for COVID-19
af: Alessandro Matarese, et al.
Udgivet: (2020-10-01)

The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes through the β-Arrestin Pathway
af: Paul Bigliardi, et al.
Udgivet: (2024-01-01)

GPCR Binding and JNK3 Activation by Arrestin-3 Have Different Structural Requirements
af: Chen Zheng, et al.
Udgivet: (2023-06-01)

Serum microRNA qPCR profiling and validation indicate upregulation of circulating miR-145-5p and miR-26a-5p in migraineurs
af: Joanna Kordacka, et al.
Udgivet: (2024-11-01)

The Absence of FAIM Leads to a Delay in Dark Adaptation and Hampers Arrestin-1 Translocation upon Light Reception in the Retina
af: Anna Sirés, et al.
Udgivet: (2023-02-01)

Gut Metabolite Trimethylamine N-Oxide Protects INS-1 β-Cell and Rat Islet Function under Diabetic Glucolipotoxic Conditions
af: Emily S. Krueger, et al.
Udgivet: (2021-12-01)

Paeonol ameliorates hippocampal neuronal damage by inhibiting GRM5/GABBR2/β-arrestin2 and activating the cAMP-PKA signaling pathway in premenstrual irritability rats
af: Enhua Wei, et al.
Udgivet: (2023-12-01)

Comparative interactome analysis of α-arrestin families in human and Drosophila
af: Kyung-Tae Lee, et al.
Udgivet: (2024-01-01)

Mechanistic Investigation of GHS-R Mediated Glucose-Stimulated Insulin Secretion in Pancreatic Islets
af: Geetali Pradhan, et al.
Udgivet: (2022-03-01)

cAMP-PKA/EPAC signaling and cancer: the interplay in tumor microenvironment
af: Hongying Zhang, et al.
Udgivet: (2024-01-01)

Posttranscriptional Regulation of Insulin Resistance: Implications for Metabolic Diseases
af: Ana Pérez-García, et al.
Udgivet: (2022-01-01)

Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro
af: Miao Liu, et al.
Udgivet: (2025-01-01)

Control of Cytoskeletal Dynamics by β-Arrestin1/Myosin Vb Signaling Regulates Endosomal Sorting and Scavenging Activity of the Atypical Chemokine Receptor ACKR2
af: Alessandro Vacchini, et al.
Udgivet: (2020-09-01)

Transmission of reduced levels of miR-34/449 from sperm to preimplantation embryos is a key step in the transgenerational epigenetic inheritance of the effects of paternal chronic social instability stress
af: Alexandre Champroux, et al.
Udgivet: (2024-12-01)

A fungal ubiquitin ligase and arrestin binding partner contribute to pathogenesis and survival during cellular stress
af: Lukas M. du Plooy, et al.
Udgivet: (2024-10-01)

Structural Insights into the Intrinsically Disordered GPCR C-Terminal Region, Major Actor in Arrestin-GPCR Interaction
af: Myriam Guillien, et al.
Udgivet: (2022-04-01)

Research progress in the role of β-arrestin 1 in the regulation of inflammatory response
af: YI Wenjing, et al.
Udgivet: (2024-12-01)

Modulation of MicroRNAs and Exosomal MicroRNAs after Dietary Interventions for Obesity and Insulin Resistance: A Narrative Review
af: Karla G. Hernández-Gómez, et al.
Udgivet: (2023-12-01)

Overcoming the Limitations of Stem Cell-Derived Beta Cells
af: Mariana V. Karimova, et al.
Udgivet: (2022-06-01)

β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor
af: Carole Daly, et al.
Udgivet: (2023-10-01)

Pharmacological Inhibition of Epac1 Averts Ferroptosis Cell Death by Preserving Mitochondrial Integrity
af: Nshunge Musheshe, et al.
Udgivet: (2022-02-01)

Astrocyte-derived exosomes regulate sperm miR-34c levels to mediate the transgenerational effects of paternal chronic social instability stress
af: Alexandre Champroux, et al.
Udgivet: (2025-12-01)

Enhanced Production and Functional Characterization of Recombinant Equine Chorionic Gonadotropin (rec-eCG) in CHO-DG44 Cells
af: Munkhzaya Byambaragchaa, et al.
Udgivet: (2025-02-01)