Glufosinate-Ammonium Induced Aberrant Histone Modifications in Mouse Sperm Are Concordant With Transcriptome in Preimplantation Embryos

Glufosinate-Ammonium Induced Aberrant Histone Modifications in Mouse Sperm Are Concordant With Transcriptome in Preimplantation Embryos

Glufosinate-ammonium (GLA) is a widely used herbicide with emerging concern over its male reproductive toxicity. Abnormalities in sperm histone modification induced by GLA exposure observed in our previous study aroused our interest in whether such alterations could further affect embryonic gene exp...

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Bibliographic Details
Main Authors: Xuan Ma, Yun Fan, Wenwen Xiao, Xingwang Ding, Weiyue Hu, Yankai Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Physiology
Subjects:
glufosinate-ammonium
H3K4me3
H3K27ac
sperm
embryo development
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.819856/full

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