Sex Differences in Adiposity and Cardiovascular Diseases
Body fat distribution is a well-established predictor of adverse medical outcomes, independent of overall adiposity. Studying body fat distribution sheds insights into the causes of obesity and provides valuable information about the development of various comorbidities. Compared to total adiposity,...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-08-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/23/16/9338 |
| _version_ | 1797409668655480832 |
|---|---|
| author | Haoyun Li Daniels Konja Luyao Wang Yu Wang |
| author_facet | Haoyun Li Daniels Konja Luyao Wang Yu Wang |
| author_sort | Haoyun Li |
| collection | DOAJ |
| description | Body fat distribution is a well-established predictor of adverse medical outcomes, independent of overall adiposity. Studying body fat distribution sheds insights into the causes of obesity and provides valuable information about the development of various comorbidities. Compared to total adiposity, body fat distribution is more closely associated with risks of cardiovascular diseases. The present review specifically focuses on the sexual dimorphism in body fat distribution, the biological clues, as well as the genetic traits that are distinct from overall obesity. Understanding the sex determinations on body fat distribution and adiposity will aid in the improvement of the prevention and treatment of cardiovascular diseases (CVD). |
| first_indexed | 2024-03-09T04:18:54Z |
| format | Article |
| id | doaj.art-57213a24e60344fa9eb04a1441d15782 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T04:18:54Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-57213a24e60344fa9eb04a1441d157822023-12-03T13:49:49ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-08-012316933810.3390/ijms23169338Sex Differences in Adiposity and Cardiovascular DiseasesHaoyun Li0Daniels Konja1Luyao Wang2Yu Wang3The State Key Laboratory of Pharmaceutical Biotechnology, Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, ChinaThe State Key Laboratory of Pharmaceutical Biotechnology, Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, ChinaThe State Key Laboratory of Pharmaceutical Biotechnology, Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, ChinaThe State Key Laboratory of Pharmaceutical Biotechnology, Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong SAR, ChinaBody fat distribution is a well-established predictor of adverse medical outcomes, independent of overall adiposity. Studying body fat distribution sheds insights into the causes of obesity and provides valuable information about the development of various comorbidities. Compared to total adiposity, body fat distribution is more closely associated with risks of cardiovascular diseases. The present review specifically focuses on the sexual dimorphism in body fat distribution, the biological clues, as well as the genetic traits that are distinct from overall obesity. Understanding the sex determinations on body fat distribution and adiposity will aid in the improvement of the prevention and treatment of cardiovascular diseases (CVD).https://www.mdpi.com/1422-0067/23/16/9338obesityadipose tissuesexual dimorphismbody fat distributioncardiovascular diseases |
| spellingShingle | Haoyun Li Daniels Konja Luyao Wang Yu Wang Sex Differences in Adiposity and Cardiovascular Diseases International Journal of Molecular Sciences obesity adipose tissue sexual dimorphism body fat distribution cardiovascular diseases |
| title | Sex Differences in Adiposity and Cardiovascular Diseases |
| title_full | Sex Differences in Adiposity and Cardiovascular Diseases |
| title_fullStr | Sex Differences in Adiposity and Cardiovascular Diseases |
| title_full_unstemmed | Sex Differences in Adiposity and Cardiovascular Diseases |
| title_short | Sex Differences in Adiposity and Cardiovascular Diseases |
| title_sort | sex differences in adiposity and cardiovascular diseases |
| topic | obesity adipose tissue sexual dimorphism body fat distribution cardiovascular diseases |
| url | https://www.mdpi.com/1422-0067/23/16/9338 |
| work_keys_str_mv | AT haoyunli sexdifferencesinadiposityandcardiovasculardiseases AT danielskonja sexdifferencesinadiposityandcardiovasculardiseases AT luyaowang sexdifferencesinadiposityandcardiovasculardiseases AT yuwang sexdifferencesinadiposityandcardiovasculardiseases |