From Antisense RNA to RNA Modification: Therapeutic Potential of RNA-Based Technologies
Therapeutic oligonucleotides interact with a target RNA via Watson-Crick complementarity, affecting RNA-processing reactions such as mRNA degradation, pre-mRNA splicing, or mRNA translation. Since they were proposed decades ago, several have been approved for clinical use to correct genetic mutation...
Main Authors: | Hironori Adachi, Martin Hengesbach, Yi-Tao Yu, Pedro Morais |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-05-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/9/5/550 |
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