Paraneoplastic Necrotizing Autoimmune Myopathy in a Patient Undergoing Laparoscopic Pancreatoduodenectomy for Distal Cholangiocarcinoma
A 73-year-old male presented with jaundice and severe muscle weakness. He was diagnosed with distal cholangiocarcinoma and paraneoplastic necrotizing autoimmune myopathy (NAM). Treatment of NAM consisted of dexamethasone pulse therapy, prednisone, and single-dose intravenous immunoglobulin. The dist...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2016-10-01
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| Series: | Case Reports in Gastroenterology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/448882 |
| _version_ | 1819029589769322496 |
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| author | Stefan van Dijk Anneke J. van der Kooi Eleonora Aronica Thomas M. van Gulik Olivier R. Busch Marc G. Besselink |
| author_facet | Stefan van Dijk Anneke J. van der Kooi Eleonora Aronica Thomas M. van Gulik Olivier R. Busch Marc G. Besselink |
| author_sort | Stefan van Dijk |
| collection | DOAJ |
| description | A 73-year-old male presented with jaundice and severe muscle weakness. He was diagnosed with distal cholangiocarcinoma and paraneoplastic necrotizing autoimmune myopathy (NAM). Treatment of NAM consisted of dexamethasone pulse therapy, prednisone, and single-dose intravenous immunoglobulin. The distal cholangiocarcinoma was resected through a total laparoscopic pancreatoduodenectomy. After hospital discharge, muscle strength initially increased postoperatively; however, pneumonia resulted in the deterioration of his general condition and death 5 months after the diagnosis of paraneoplastic NAM. |
| first_indexed | 2024-12-21T06:16:40Z |
| format | Article |
| id | doaj.art-5724073e81ba46d59670c3c102ca5e02 |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-12-21T06:16:40Z |
| publishDate | 2016-10-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-5724073e81ba46d59670c3c102ca5e022022-12-21T19:13:23ZengKarger PublishersCase Reports in Gastroenterology1662-06312016-10-0110352553010.1159/000448882448882Paraneoplastic Necrotizing Autoimmune Myopathy in a Patient Undergoing Laparoscopic Pancreatoduodenectomy for Distal CholangiocarcinomaStefan van DijkAnneke J. van der KooiEleonora AronicaThomas M. van GulikOlivier R. BuschMarc G. BesselinkA 73-year-old male presented with jaundice and severe muscle weakness. He was diagnosed with distal cholangiocarcinoma and paraneoplastic necrotizing autoimmune myopathy (NAM). Treatment of NAM consisted of dexamethasone pulse therapy, prednisone, and single-dose intravenous immunoglobulin. The distal cholangiocarcinoma was resected through a total laparoscopic pancreatoduodenectomy. After hospital discharge, muscle strength initially increased postoperatively; however, pneumonia resulted in the deterioration of his general condition and death 5 months after the diagnosis of paraneoplastic NAM.http://www.karger.com/Article/FullText/448882Paraneoplastic necrotizing autoimmune myopathyCholangiocarcinomaLaparoscopic pancreatoduodenectomy |
| spellingShingle | Stefan van Dijk Anneke J. van der Kooi Eleonora Aronica Thomas M. van Gulik Olivier R. Busch Marc G. Besselink Paraneoplastic Necrotizing Autoimmune Myopathy in a Patient Undergoing Laparoscopic Pancreatoduodenectomy for Distal Cholangiocarcinoma Case Reports in Gastroenterology Paraneoplastic necrotizing autoimmune myopathy Cholangiocarcinoma Laparoscopic pancreatoduodenectomy |
| title | Paraneoplastic Necrotizing Autoimmune Myopathy in a Patient Undergoing Laparoscopic Pancreatoduodenectomy for Distal Cholangiocarcinoma |
| title_full | Paraneoplastic Necrotizing Autoimmune Myopathy in a Patient Undergoing Laparoscopic Pancreatoduodenectomy for Distal Cholangiocarcinoma |
| title_fullStr | Paraneoplastic Necrotizing Autoimmune Myopathy in a Patient Undergoing Laparoscopic Pancreatoduodenectomy for Distal Cholangiocarcinoma |
| title_full_unstemmed | Paraneoplastic Necrotizing Autoimmune Myopathy in a Patient Undergoing Laparoscopic Pancreatoduodenectomy for Distal Cholangiocarcinoma |
| title_short | Paraneoplastic Necrotizing Autoimmune Myopathy in a Patient Undergoing Laparoscopic Pancreatoduodenectomy for Distal Cholangiocarcinoma |
| title_sort | paraneoplastic necrotizing autoimmune myopathy in a patient undergoing laparoscopic pancreatoduodenectomy for distal cholangiocarcinoma |
| topic | Paraneoplastic necrotizing autoimmune myopathy Cholangiocarcinoma Laparoscopic pancreatoduodenectomy |
| url | http://www.karger.com/Article/FullText/448882 |
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