Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke

Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke

The effects of thrombolysis therapy in stroke on structural connectivity are not well understood. Here, the authors show with causal mediation analysis that the clinical benefits of thrombolysis in anterior circulation stroke are mediated via structural connectivity.

Bibliographic Details
Main Authors:	Eckhard Schlemm, Thies Ingwersen, Alina Königsberg, Florent Boutitie, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Ivana Galinovic, Robin Lemmens, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Josep Puig, Claus Z. Simonsen, Vincent Thijs, Anke Wouters, Christian Gerloff, Götz Thomalla, Bastian Cheng
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-05-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-021-22786-w

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