Giant hyperplastic gastric polyp: A diagnostic dilemma!!

Gastric hyperplastic polyps (GHP) account for a majority of benign gastric polyps. Most of the GHPs are <2 cm, asymptomatic, and incidentally detected on endoscopy or radiologically. With increasing size, these polyps manifest as upper gastrointestinal bleeding, iron deficiency anemia, and gastri...

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Main Authors: Ashish Jain, Dimple Chaudhary, Surbhi Goyal, Anil K Agarwal, Puja Sakhuja
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2022;volume=65;issue=4;spage=914;epage=917;aulast=Jain
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author Ashish Jain
Dimple Chaudhary
Surbhi Goyal
Anil K Agarwal
Puja Sakhuja
author_facet Ashish Jain
Dimple Chaudhary
Surbhi Goyal
Anil K Agarwal
Puja Sakhuja
author_sort Ashish Jain
collection DOAJ
description Gastric hyperplastic polyps (GHP) account for a majority of benign gastric polyps. Most of the GHPs are <2 cm, asymptomatic, and incidentally detected on endoscopy or radiologically. With increasing size, these polyps manifest as upper gastrointestinal bleeding, iron deficiency anemia, and gastric outlet obstruction (GOO). We report an unusual case of giant GHP simulating gastric carcinoma and posing as a diagnostic challenge for the surgeons emphasizing the diagnostic role of histopathology. A 46-year-old female presented with clinical features of progressive GOO for 1 year. Endoscopy revealed an eccentric proliferative lesion in the antrum. Computed tomography showed a polypoidal, enhancing mural thickening involving distal body and antro-pyloric region measuring 8.4 cm × 6.6 cm × 1.8 cm. Subtotal gastrectomy was done in view of clinical features of GOO and having a clinical suspicion of malignancy. Gross examination showed a giant sessile hyperplastic polyp with lobulated surface. Microscopy revealed features of a large, sessile hyperplastic polyp without any evidence of dysplasia. The patient was symptomatically relieved and is on follow-up. To conclude, giant GHPs can mimic gastric carcinoma on endoscopy and radiology. The possibility of giant GHP should be kept in mind in the presence of an intensely contrast-enhancing polypoidal lesion in the gastric antrum. Long-term endoscopic follow-up is recommended.
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spelling doaj.art-572735f6b74b43d3a88c0f8b063a7f112023-01-03T09:56:32ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292022-01-0165491491710.4103/ijpm.ijpm_136_21Giant hyperplastic gastric polyp: A diagnostic dilemma!!Ashish JainDimple ChaudharySurbhi GoyalAnil K AgarwalPuja SakhujaGastric hyperplastic polyps (GHP) account for a majority of benign gastric polyps. Most of the GHPs are <2 cm, asymptomatic, and incidentally detected on endoscopy or radiologically. With increasing size, these polyps manifest as upper gastrointestinal bleeding, iron deficiency anemia, and gastric outlet obstruction (GOO). We report an unusual case of giant GHP simulating gastric carcinoma and posing as a diagnostic challenge for the surgeons emphasizing the diagnostic role of histopathology. A 46-year-old female presented with clinical features of progressive GOO for 1 year. Endoscopy revealed an eccentric proliferative lesion in the antrum. Computed tomography showed a polypoidal, enhancing mural thickening involving distal body and antro-pyloric region measuring 8.4 cm × 6.6 cm × 1.8 cm. Subtotal gastrectomy was done in view of clinical features of GOO and having a clinical suspicion of malignancy. Gross examination showed a giant sessile hyperplastic polyp with lobulated surface. Microscopy revealed features of a large, sessile hyperplastic polyp without any evidence of dysplasia. The patient was symptomatically relieved and is on follow-up. To conclude, giant GHPs can mimic gastric carcinoma on endoscopy and radiology. The possibility of giant GHP should be kept in mind in the presence of an intensely contrast-enhancing polypoidal lesion in the gastric antrum. Long-term endoscopic follow-up is recommended.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2022;volume=65;issue=4;spage=914;epage=917;aulast=Jaindysplasiagastric polyphyperplastic polyp
spellingShingle Ashish Jain
Dimple Chaudhary
Surbhi Goyal
Anil K Agarwal
Puja Sakhuja
Giant hyperplastic gastric polyp: A diagnostic dilemma!!
Indian Journal of Pathology and Microbiology
dysplasia
gastric polyp
hyperplastic polyp
title Giant hyperplastic gastric polyp: A diagnostic dilemma!!
title_full Giant hyperplastic gastric polyp: A diagnostic dilemma!!
title_fullStr Giant hyperplastic gastric polyp: A diagnostic dilemma!!
title_full_unstemmed Giant hyperplastic gastric polyp: A diagnostic dilemma!!
title_short Giant hyperplastic gastric polyp: A diagnostic dilemma!!
title_sort giant hyperplastic gastric polyp a diagnostic dilemma
topic dysplasia
gastric polyp
hyperplastic polyp
url http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2022;volume=65;issue=4;spage=914;epage=917;aulast=Jain
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AT dimplechaudhary gianthyperplasticgastricpolypadiagnosticdilemma
AT surbhigoyal gianthyperplasticgastricpolypadiagnosticdilemma
AT anilkagarwal gianthyperplasticgastricpolypadiagnosticdilemma
AT pujasakhuja gianthyperplasticgastricpolypadiagnosticdilemma