Emphysematous pyelonephritis - case report and review of literature

Introduction. Emphysematous pyelonephritis (EPN) is a severe, potentially fatal necrotizing infection of the kidney with the clinical picture ranging from the mild abdominal pain and discomfort to the septic shock and multiorgan failure. We presented here a case of EPN in a poorly controlled diabeti...

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Main Authors: Ćelić Dejan, Božić Dušan, Petrović Kosta, Živojinov Srđan, Đurđević-Mirković Tatjana, Popović Milica
Format: Article
Language:English
Published: Military Health Department, Ministry of Defance, Serbia 2017-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600312C.pdf
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author Ćelić Dejan
Božić Dušan
Petrović Kosta
Živojinov Srđan
Đurđević-Mirković Tatjana
Popović Milica
author_facet Ćelić Dejan
Božić Dušan
Petrović Kosta
Živojinov Srđan
Đurđević-Mirković Tatjana
Popović Milica
author_sort Ćelić Dejan
collection DOAJ
description Introduction. Emphysematous pyelonephritis (EPN) is a severe, potentially fatal necrotizing infection of the kidney with the clinical picture ranging from the mild abdominal pain and discomfort to the septic shock and multiorgan failure. We presented here a case of EPN in a poorly controlled diabetic patient that was the first registered case of EPN in our clinic for more than ten years. Case report. A 78-year-old diabetic male patient was referred to the Clinic for Nephrology and Clinical Immunology of the Clinical Center of Vojvodina, Novi Sad, Serbia, with weakness, malaise, abdominal discomfort and reduced daily urine volume. After complete physical exam, laboratory work up, echosonographic and computed tomography scanning we diagnosed the patient with EPN class IV, according to the Huang and Tseng classification, with the presence of 5 risk factors for mortality (systolic blood pressure below 90 mmHg, altered consciousness, thrombocytopenia, elevated serum creatinine level, bilateral disease). Treatment with conservative therapy and percutaneous drainage was not successful, further deteorioration of the patient status ensued so the patient passed away on the 8th day of hospitalization due to the development of septic shock with multiorgan failure that was refractory to all measures that were instituted. Conclusion. EPN is a severe, potentially fatal necrotizing inflammation of the kidney and surrounding tissue. Management and prognosis of this disease depends on the clinical status, risk factors and radiological classification of the disease.
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spelling doaj.art-57281516519f42c7b7e638bb1715b28b2022-12-21T19:34:44ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202017-01-0174121170117310.2298/VSP160328312C0042-84501600312CEmphysematous pyelonephritis - case report and review of literatureĆelić Dejan0Božić Dušan1Petrović Kosta2Živojinov Srđan3Đurđević-Mirković Tatjana4Popović Milica5Clinical Center of Vojvodina, Clinic for Nephrology and Clinical Immunology, Novi Sad + Faculty of Medicine, Novi SadClinical Center of Vojvodina, Clinic for Nephrology and Clinical Immunology, Novi Sad + Faculty of Medicine, Novi SadFaculty of Medicine, Novi Sad + Clinical Center of Vojvodina, Center for Radiology, Novi SadFaculty of Medicine, Novi Sad + Clinical Center of Vojvodina, Clinic for Urology, Novi SadClinical Center of Vojvodina, Clinic for Nephrology and Clinical Immunology, Novi Sad + Faculty of Medicine, Novi SadClinical Center of Vojvodina, Clinic for Nephrology and Clinical Immunology, Novi Sad + Faculty of Medicine, Novi SadIntroduction. Emphysematous pyelonephritis (EPN) is a severe, potentially fatal necrotizing infection of the kidney with the clinical picture ranging from the mild abdominal pain and discomfort to the septic shock and multiorgan failure. We presented here a case of EPN in a poorly controlled diabetic patient that was the first registered case of EPN in our clinic for more than ten years. Case report. A 78-year-old diabetic male patient was referred to the Clinic for Nephrology and Clinical Immunology of the Clinical Center of Vojvodina, Novi Sad, Serbia, with weakness, malaise, abdominal discomfort and reduced daily urine volume. After complete physical exam, laboratory work up, echosonographic and computed tomography scanning we diagnosed the patient with EPN class IV, according to the Huang and Tseng classification, with the presence of 5 risk factors for mortality (systolic blood pressure below 90 mmHg, altered consciousness, thrombocytopenia, elevated serum creatinine level, bilateral disease). Treatment with conservative therapy and percutaneous drainage was not successful, further deteorioration of the patient status ensued so the patient passed away on the 8th day of hospitalization due to the development of septic shock with multiorgan failure that was refractory to all measures that were instituted. Conclusion. EPN is a severe, potentially fatal necrotizing inflammation of the kidney and surrounding tissue. Management and prognosis of this disease depends on the clinical status, risk factors and radiological classification of the disease.http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600312C.pdfpyelonephritisemphysemadiabetes mellitus, type 1drainagetreatment outcome
spellingShingle Ćelić Dejan
Božić Dušan
Petrović Kosta
Živojinov Srđan
Đurđević-Mirković Tatjana
Popović Milica
Emphysematous pyelonephritis - case report and review of literature
Vojnosanitetski Pregled
pyelonephritis
emphysema
diabetes mellitus, type 1
drainage
treatment outcome
title Emphysematous pyelonephritis - case report and review of literature
title_full Emphysematous pyelonephritis - case report and review of literature
title_fullStr Emphysematous pyelonephritis - case report and review of literature
title_full_unstemmed Emphysematous pyelonephritis - case report and review of literature
title_short Emphysematous pyelonephritis - case report and review of literature
title_sort emphysematous pyelonephritis case report and review of literature
topic pyelonephritis
emphysema
diabetes mellitus, type 1
drainage
treatment outcome
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600312C.pdf
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