Three New Abietane-Type Diterpenoids from Callicarpa macrophylla Vahl.
Three new abietane-type diterpenoids, named callicapoic acid M3 (1), callicapoic acid M4 (2) and callicapoic acid M5 (3), were isolated from the Callicarpa macrophylla Vahl. Their structures were established by spectroscopic techniques (IR, UV, MS, 1D and 2D NMR). All the isolated three compounds we...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-05-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/22/5/842 |
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| author | Zhen-Hui Wang Chao Niu De-Jun Zhou Ji-Chuan Kong Wen-Kui Zhang |
| author_facet | Zhen-Hui Wang Chao Niu De-Jun Zhou Ji-Chuan Kong Wen-Kui Zhang |
| author_sort | Zhen-Hui Wang |
| collection | DOAJ |
| description | Three new abietane-type diterpenoids, named callicapoic acid M3 (1), callicapoic acid M4 (2) and callicapoic acid M5 (3), were isolated from the Callicarpa macrophylla Vahl. Their structures were established by spectroscopic techniques (IR, UV, MS, 1D and 2D NMR). All the isolated three compounds were evaluated for inhibitory activity on NO production in LPS-activated RAW 264.7 macrophage cells by using MTT assays. Compounds 1, 2 and 3 showed potent inhibitory activity, with inhibition rates of 34.47–40.13%. |
| first_indexed | 2024-12-22T14:24:49Z |
| format | Article |
| id | doaj.art-5728fa09fad147fda42507be9aaf1a5f |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-22T14:24:49Z |
| publishDate | 2017-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-5728fa09fad147fda42507be9aaf1a5f2022-12-21T18:22:53ZengMDPI AGMolecules1420-30492017-05-0122584210.3390/molecules22050842molecules22050842Three New Abietane-Type Diterpenoids from Callicarpa macrophylla Vahl.Zhen-Hui Wang0Chao Niu1De-Jun Zhou2Ji-Chuan Kong3Wen-Kui Zhang4College of Medicine, Henan Polytechnic University, Jiaozuo 454000, ChinaCollege of Medicine, Henan Polytechnic University, Jiaozuo 454000, ChinaCollege of Medicine, Henan Polytechnic University, Jiaozuo 454000, ChinaCollege of Medicine, Henan Polytechnic University, Jiaozuo 454000, ChinaCollege of Medicine, Henan Polytechnic University, Jiaozuo 454000, ChinaThree new abietane-type diterpenoids, named callicapoic acid M3 (1), callicapoic acid M4 (2) and callicapoic acid M5 (3), were isolated from the Callicarpa macrophylla Vahl. Their structures were established by spectroscopic techniques (IR, UV, MS, 1D and 2D NMR). All the isolated three compounds were evaluated for inhibitory activity on NO production in LPS-activated RAW 264.7 macrophage cells by using MTT assays. Compounds 1, 2 and 3 showed potent inhibitory activity, with inhibition rates of 34.47–40.13%.http://www.mdpi.com/1420-3049/22/5/842Callicarpa macrophylla Vahl.abietane-type diterpenoidsNMRanti-inflammatory activity |
| spellingShingle | Zhen-Hui Wang Chao Niu De-Jun Zhou Ji-Chuan Kong Wen-Kui Zhang Three New Abietane-Type Diterpenoids from Callicarpa macrophylla Vahl. Molecules Callicarpa macrophylla Vahl. abietane-type diterpenoids NMR anti-inflammatory activity |
| title | Three New Abietane-Type Diterpenoids from Callicarpa macrophylla Vahl. |
| title_full | Three New Abietane-Type Diterpenoids from Callicarpa macrophylla Vahl. |
| title_fullStr | Three New Abietane-Type Diterpenoids from Callicarpa macrophylla Vahl. |
| title_full_unstemmed | Three New Abietane-Type Diterpenoids from Callicarpa macrophylla Vahl. |
| title_short | Three New Abietane-Type Diterpenoids from Callicarpa macrophylla Vahl. |
| title_sort | three new abietane type diterpenoids from callicarpa macrophylla vahl |
| topic | Callicarpa macrophylla Vahl. abietane-type diterpenoids NMR anti-inflammatory activity |
| url | http://www.mdpi.com/1420-3049/22/5/842 |
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