Integrative metagenomic and metabolomic analyses reveal the role of gut microbiota in antibody-mediated renal allograft rejection

Integrative metagenomic and metabolomic analyses reveal the role of gut microbiota in antibody-mediated renal allograft rejection

Abstract Background Antibody-mediated rejection (AMR) remains one of the major barriers for graft survival after kidney transplantation. Our previous study suggested a gut microbiota dysbiosis in kidney transplantation recipients with AMR. However, alternations in gut microbial function and structur...

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Bibliographic Details
Main Authors: Xin Li, Ruoying Li, Bingqing Ji, Lili Zhao, Junpeng Wang, Tianzhong Yan
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Translational Medicine
Subjects:
Antibody-mediated rejection
Gut microbiota
Metagenomics
Fecal metabolites
Kidney transplantation
Online Access:https://doi.org/10.1186/s12967-022-03825-6

Internet

https://doi.org/10.1186/s12967-022-03825-6

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