The Multifaceted Roles of Diet, Microbes, and Metabolites in Cancer

Many studies performed to date have implicated select microbes and dietary factors in a variety of cancers, yet the complexity of both these diseases and the relationship between these factors has limited the ability to translate findings into therapies and preventative guidelines. Here we begin by...

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Main Authors: Heather Armstrong, Michael Bording-Jorgensen, Eytan Wine
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/4/767
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author Heather Armstrong
Michael Bording-Jorgensen
Eytan Wine
author_facet Heather Armstrong
Michael Bording-Jorgensen
Eytan Wine
author_sort Heather Armstrong
collection DOAJ
description Many studies performed to date have implicated select microbes and dietary factors in a variety of cancers, yet the complexity of both these diseases and the relationship between these factors has limited the ability to translate findings into therapies and preventative guidelines. Here we begin by discussing recently published studies relating to dietary factors, such as vitamins and chemical compounds used as ingredients, and their contribution to cancer development. We further review recent studies, which display evidence of the microbial-diet interaction in the context of cancer. The field continues to advance our understanding of the development of select cancers and how dietary factors are related to the development, prevention, and treatment of these cancers. Finally, we highlight the science available in the discussion of common misconceptions with regards to cancer and diet. We conclude this review with thoughts on where we believe future research should focus in order to provide the greatest impact towards human health and preventative medicine.
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spelling doaj.art-572f7694dd454741885f8a4b63216aa42023-12-11T16:51:17ZengMDPI AGCancers2072-66942021-02-0113476710.3390/cancers13040767The Multifaceted Roles of Diet, Microbes, and Metabolites in CancerHeather Armstrong0Michael Bording-Jorgensen1Eytan Wine2CEGIIR, University of Alberta, Edmonton, AB T6G 2X8, CanadaCEGIIR, University of Alberta, Edmonton, AB T6G 2X8, CanadaCEGIIR, University of Alberta, Edmonton, AB T6G 2X8, CanadaMany studies performed to date have implicated select microbes and dietary factors in a variety of cancers, yet the complexity of both these diseases and the relationship between these factors has limited the ability to translate findings into therapies and preventative guidelines. Here we begin by discussing recently published studies relating to dietary factors, such as vitamins and chemical compounds used as ingredients, and their contribution to cancer development. We further review recent studies, which display evidence of the microbial-diet interaction in the context of cancer. The field continues to advance our understanding of the development of select cancers and how dietary factors are related to the development, prevention, and treatment of these cancers. Finally, we highlight the science available in the discussion of common misconceptions with regards to cancer and diet. We conclude this review with thoughts on where we believe future research should focus in order to provide the greatest impact towards human health and preventative medicine.https://www.mdpi.com/2072-6694/13/4/767cancerdietnutritionmicrobesmisconceptionsrisk factors
spellingShingle Heather Armstrong
Michael Bording-Jorgensen
Eytan Wine
The Multifaceted Roles of Diet, Microbes, and Metabolites in Cancer
Cancers
cancer
diet
nutrition
microbes
misconceptions
risk factors
title The Multifaceted Roles of Diet, Microbes, and Metabolites in Cancer
title_full The Multifaceted Roles of Diet, Microbes, and Metabolites in Cancer
title_fullStr The Multifaceted Roles of Diet, Microbes, and Metabolites in Cancer
title_full_unstemmed The Multifaceted Roles of Diet, Microbes, and Metabolites in Cancer
title_short The Multifaceted Roles of Diet, Microbes, and Metabolites in Cancer
title_sort multifaceted roles of diet microbes and metabolites in cancer
topic cancer
diet
nutrition
microbes
misconceptions
risk factors
url https://www.mdpi.com/2072-6694/13/4/767
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