Hospital readmissions and emergency department re-presentation of COVID-19 patients: a systematic review
Objective. To characterize the frequency, causes, and predictors of readmissions of COVID-19 patients after discharge from heath facilities or emergency departments, interventions used to reduce readmissions, and outcomes of COVID-19 patients discharged from such settings. Methods. We performed a sy...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Pan American Health Organization
2022-10-01
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| Series: | Revista Panamericana de Salud Pública |
| Subjects: | |
| Online Access: | https://iris.paho.org/handle/10665.2/56469 |
| _version_ | 1817984751801204736 |
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| author | Sasha Peiris Joseph L. Nates Joao Toledo Yeh-Li Ho Ojino Sosa Victoria Stanford Sylvain Aldighieri Ludovic Reveiz |
| author_facet | Sasha Peiris Joseph L. Nates Joao Toledo Yeh-Li Ho Ojino Sosa Victoria Stanford Sylvain Aldighieri Ludovic Reveiz |
| author_sort | Sasha Peiris |
| collection | DOAJ |
| description | Objective. To characterize the frequency, causes, and predictors of readmissions of COVID-19 patients after discharge from heath facilities or emergency departments, interventions used to reduce readmissions, and outcomes of COVID-19 patients discharged from such settings.
Methods. We performed a systematic review for case series and observational studies published between January 2020 and April 2021 in PubMed, Embase, LILACS, and MedRxiv, reporting the frequency, causes, or risk factors for readmission of COVID-19 survivors/patients. We conducted a narrative synthesis and assessed the methodological quality using the JBI critical appraisal checklist.
Results. We identified 44 studies including data from 10 countries. The overall 30-day median readmission rate was 7.1%. Readmissions varied with the length of follow-up, occurring <10.5%, <14.5%, <21.5%, and <30%, respectively, for 10, 30, 60, and 253 days following discharge. Among those followed up for 30 and 60 days, the median time from discharge to readmission was 3 days and 8–11 days, respectively. The significant risk factor associated with readmission was having shorter length of stay, and the important causes included respiratory or thromboembolic events and chronic illnesses. Emergency department re-presentation was >20% in four studies. Risk factors associated with mortality were male gender, advanced age, and comorbidities.
Conclusions. Readmission of COVID-19 survivors is frequent, and post-discharge mortality is significant in specific populations. There is an urgent need to further examine underlying reasons for early readmission and to prevent additional readmissions and adverse outcomes in COVID-19 survivors. |
| first_indexed | 2024-04-13T23:48:56Z |
| format | Article |
| id | doaj.art-572fe69fef2d4f1182f3ad44b67f7548 |
| institution | Directory Open Access Journal |
| issn | 1020-4989 1680-5348 |
| language | English |
| last_indexed | 2024-04-13T23:48:56Z |
| publishDate | 2022-10-01 |
| publisher | Pan American Health Organization |
| record_format | Article |
| series | Revista Panamericana de Salud Pública |
| spelling | doaj.art-572fe69fef2d4f1182f3ad44b67f75482022-12-22T02:24:11ZengPan American Health OrganizationRevista Panamericana de Salud Pública1020-49891680-53482022-10-014614211210.26633/RPSP.2022.142rpspHospital readmissions and emergency department re-presentation of COVID-19 patients: a systematic reviewSasha Peiris0Joseph L. Nates1Joao Toledo2Yeh-Li Ho3Ojino Sosa4Victoria Stanford5Sylvain Aldighieri6Ludovic Reveiz7Pan American Health Organization, Washington, D.C., United States of AmericaThe University of Texas, Houston, United States of AmericaPan American Health Organization, Washington, D.C., United States of AmericaUniversidade de São Paulo, São Paulo, BrazilInstituto Mexicano del Seguro Social, Mexico City, MexicoPan American Health Organization, Washington, D.C., United States of AmericaPan American Health Organization, Washington, D.C., United States of AmericaPan American Health Organization, Washington, D.C., United States of AmericaObjective. To characterize the frequency, causes, and predictors of readmissions of COVID-19 patients after discharge from heath facilities or emergency departments, interventions used to reduce readmissions, and outcomes of COVID-19 patients discharged from such settings. Methods. We performed a systematic review for case series and observational studies published between January 2020 and April 2021 in PubMed, Embase, LILACS, and MedRxiv, reporting the frequency, causes, or risk factors for readmission of COVID-19 survivors/patients. We conducted a narrative synthesis and assessed the methodological quality using the JBI critical appraisal checklist. Results. We identified 44 studies including data from 10 countries. The overall 30-day median readmission rate was 7.1%. Readmissions varied with the length of follow-up, occurring <10.5%, <14.5%, <21.5%, and <30%, respectively, for 10, 30, 60, and 253 days following discharge. Among those followed up for 30 and 60 days, the median time from discharge to readmission was 3 days and 8–11 days, respectively. The significant risk factor associated with readmission was having shorter length of stay, and the important causes included respiratory or thromboembolic events and chronic illnesses. Emergency department re-presentation was >20% in four studies. Risk factors associated with mortality were male gender, advanced age, and comorbidities. Conclusions. Readmission of COVID-19 survivors is frequent, and post-discharge mortality is significant in specific populations. There is an urgent need to further examine underlying reasons for early readmission and to prevent additional readmissions and adverse outcomes in COVID-19 survivors.https://iris.paho.org/handle/10665.2/56469covid-19sars-cov-2systematic reviewpatient readmissionemergency service, hospitalmortality |
| spellingShingle | Sasha Peiris Joseph L. Nates Joao Toledo Yeh-Li Ho Ojino Sosa Victoria Stanford Sylvain Aldighieri Ludovic Reveiz Hospital readmissions and emergency department re-presentation of COVID-19 patients: a systematic review Revista Panamericana de Salud Pública covid-19 sars-cov-2 systematic review patient readmission emergency service, hospital mortality |
| title | Hospital readmissions and emergency department re-presentation of COVID-19 patients: a systematic review |
| title_full | Hospital readmissions and emergency department re-presentation of COVID-19 patients: a systematic review |
| title_fullStr | Hospital readmissions and emergency department re-presentation of COVID-19 patients: a systematic review |
| title_full_unstemmed | Hospital readmissions and emergency department re-presentation of COVID-19 patients: a systematic review |
| title_short | Hospital readmissions and emergency department re-presentation of COVID-19 patients: a systematic review |
| title_sort | hospital readmissions and emergency department re presentation of covid 19 patients a systematic review |
| topic | covid-19 sars-cov-2 systematic review patient readmission emergency service, hospital mortality |
| url | https://iris.paho.org/handle/10665.2/56469 |
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