Sequential Transplantation of Haploidentical Stem Cell and Unrelated Cord Blood With Using ATG/PTCY Increases Survival of Relapsed/Refractory Hematologic Malignancies

Sequential Transplantation of Haploidentical Stem Cell and Unrelated Cord Blood With Using ATG/PTCY Increases Survival of Relapsed/Refractory Hematologic Malignancies

Allogeneic haploidentical HSCT (haplo-HSCT) and unrelated umbilical cord blood transplantation(UCBT)are used in patients lacking HLA-identical sibling or unrelated donors. With myeloablative condition and GVHD prophylaxis of using low-dose ATG and post-transplantation cyclophosphamide (PTCY), we con...

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Bibliographic Details
Main Authors: Hua Li, Xiaofan Li, Yiling Chen, Duihong Li, Xianling Chen, Zhijuan Zhu, Yiting Wang, Jiafu Huang, Ping Chen, Yuanzhong Chen, Nainong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
sequential transplantation
relapsed/refractory hematologic malignancies
post-transplant cyclophosphamide
umbilical cord blood transplantation
low-dose ATG
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.733326/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.733326/full

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