Dietary lutein supplementation protects against ultraviolet-radiation-induced erythema: Results of a randomized double-blind placebo-controlled study
Various studies showed promising photoprotective and anti-aging effects of lutein, but it was mostly investigated in combination with other antioxidants, and some study results are contradictory. The aim of this randomized, double-blind placebo-controlled intervention was to investigate the effects...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-12-01
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| Series: | Journal of Functional Foods |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464620304898 |
| _version_ | 1818953684613070848 |
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| author | Katja Žmitek Janko Žmitek Mirjam Rogl Butina Hristo Hristov Tina Pogačnik Igor Pravst |
| author_facet | Katja Žmitek Janko Žmitek Mirjam Rogl Butina Hristo Hristov Tina Pogačnik Igor Pravst |
| author_sort | Katja Žmitek |
| collection | DOAJ |
| description | Various studies showed promising photoprotective and anti-aging effects of lutein, but it was mostly investigated in combination with other antioxidants, and some study results are contradictory. The aim of this randomized, double-blind placebo-controlled intervention was to investigate the effects of dietary lutein supplementation on minimal erythema dose (MED) as a measure of skin’s photoprotective potential, and other skin parameters. Thirty healthy women received supplementation of lutein (20 mg/day; liquid formulation) or placebo for 12 weeks. In the test group, MED was significantly increased, indicating greater individual’s resistance to the production of erythema following UV radiation. The overall treatment effect was 0.114 J/cm2 corresponding to a relative increase of photoprotective activity of 22%. On the other hand, we were unable to confirm supportive effects for skin regeneration. Study findings show that dietary supplementation with lutein improved skin photoprotective potential and could contribute to skin defense against UVR-mediated skin damage. |
| first_indexed | 2024-12-20T10:10:11Z |
| format | Article |
| id | doaj.art-57394af82ce84cd1b8216e852cb8887c |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-20T10:10:11Z |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-57394af82ce84cd1b8216e852cb8887c2022-12-21T19:44:10ZengElsevierJournal of Functional Foods1756-46462020-12-0175104265Dietary lutein supplementation protects against ultraviolet-radiation-induced erythema: Results of a randomized double-blind placebo-controlled studyKatja Žmitek0Janko Žmitek1Mirjam Rogl Butina2Hristo Hristov3Tina Pogačnik4Igor Pravst5VIST-Higher School of Applied Sciences, Institute of Cosmetics, Gerbičeva ulica 51a, SI-1000 Ljubljana, Slovenia; Nutrition Institute, Tržaška cesta 40, SI-1000 Ljubljana, Slovenia; Corresponding author at: VIST-Higher School of Applied Sciences, Institute of Cosmetics, Gerbičeva ulica 51a, SI-1000 Ljubljana, Slovenia.VIST-Higher School of Applied Sciences, Institute of Cosmetics, Gerbičeva ulica 51a, SI-1000 Ljubljana, SloveniaVIST-Higher School of Applied Sciences, Institute of Cosmetics, Gerbičeva ulica 51a, SI-1000 Ljubljana, Slovenia; Dermatologija Rogl Fabjan, Derčeva ulica 35, SI-1000 Ljubljana, SloveniaNutrition Institute, Tržaška cesta 40, SI-1000 Ljubljana, SloveniaVIST-Higher School of Applied Sciences, Institute of Cosmetics, Gerbičeva ulica 51a, SI-1000 Ljubljana, SloveniaVIST-Higher School of Applied Sciences, Institute of Cosmetics, Gerbičeva ulica 51a, SI-1000 Ljubljana, Slovenia; Nutrition Institute, Tržaška cesta 40, SI-1000 Ljubljana, SloveniaVarious studies showed promising photoprotective and anti-aging effects of lutein, but it was mostly investigated in combination with other antioxidants, and some study results are contradictory. The aim of this randomized, double-blind placebo-controlled intervention was to investigate the effects of dietary lutein supplementation on minimal erythema dose (MED) as a measure of skin’s photoprotective potential, and other skin parameters. Thirty healthy women received supplementation of lutein (20 mg/day; liquid formulation) or placebo for 12 weeks. In the test group, MED was significantly increased, indicating greater individual’s resistance to the production of erythema following UV radiation. The overall treatment effect was 0.114 J/cm2 corresponding to a relative increase of photoprotective activity of 22%. On the other hand, we were unable to confirm supportive effects for skin regeneration. Study findings show that dietary supplementation with lutein improved skin photoprotective potential and could contribute to skin defense against UVR-mediated skin damage.http://www.sciencedirect.com/science/article/pii/S1756464620304898LuteinMinimal erythema dosePhotoprotective activityViscoelasticityDermal densityCarotenoids |
| spellingShingle | Katja Žmitek Janko Žmitek Mirjam Rogl Butina Hristo Hristov Tina Pogačnik Igor Pravst Dietary lutein supplementation protects against ultraviolet-radiation-induced erythema: Results of a randomized double-blind placebo-controlled study Journal of Functional Foods Lutein Minimal erythema dose Photoprotective activity Viscoelasticity Dermal density Carotenoids |
| title | Dietary lutein supplementation protects against ultraviolet-radiation-induced erythema: Results of a randomized double-blind placebo-controlled study |
| title_full | Dietary lutein supplementation protects against ultraviolet-radiation-induced erythema: Results of a randomized double-blind placebo-controlled study |
| title_fullStr | Dietary lutein supplementation protects against ultraviolet-radiation-induced erythema: Results of a randomized double-blind placebo-controlled study |
| title_full_unstemmed | Dietary lutein supplementation protects against ultraviolet-radiation-induced erythema: Results of a randomized double-blind placebo-controlled study |
| title_short | Dietary lutein supplementation protects against ultraviolet-radiation-induced erythema: Results of a randomized double-blind placebo-controlled study |
| title_sort | dietary lutein supplementation protects against ultraviolet radiation induced erythema results of a randomized double blind placebo controlled study |
| topic | Lutein Minimal erythema dose Photoprotective activity Viscoelasticity Dermal density Carotenoids |
| url | http://www.sciencedirect.com/science/article/pii/S1756464620304898 |
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