Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleep
Joint scRNA-seq and proteomic analysis of the hypothalamus, cortex, and brainstem in mice provides insight into the cellular and molecular underpinnings of sleep homeostasis.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-08-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03800-3 |
| _version_ | 1811340290614624256 |
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| author | Pawan K. Jha Utham K. Valekunja Sandipan Ray Mathieu Nollet Akhilesh B. Reddy |
| author_facet | Pawan K. Jha Utham K. Valekunja Sandipan Ray Mathieu Nollet Akhilesh B. Reddy |
| author_sort | Pawan K. Jha |
| collection | DOAJ |
| description | Joint scRNA-seq and proteomic analysis of the hypothalamus, cortex, and brainstem in mice provides insight into the cellular and molecular underpinnings of sleep homeostasis. |
| first_indexed | 2024-04-13T18:39:43Z |
| format | Article |
| id | doaj.art-573a0325ad6046f29797f9510e6f15f2 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-04-13T18:39:43Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-573a0325ad6046f29797f9510e6f15f22022-12-22T02:34:46ZengNature PortfolioCommunications Biology2399-36422022-08-015111610.1038/s42003-022-03800-3Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleepPawan K. Jha0Utham K. Valekunja1Sandipan Ray2Mathieu Nollet3Akhilesh B. Reddy4Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of PennsylvaniaDepartment of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of PennsylvaniaDepartment of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of PennsylvaniaDepartment of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of PennsylvaniaDepartment of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of PennsylvaniaJoint scRNA-seq and proteomic analysis of the hypothalamus, cortex, and brainstem in mice provides insight into the cellular and molecular underpinnings of sleep homeostasis.https://doi.org/10.1038/s42003-022-03800-3 |
| spellingShingle | Pawan K. Jha Utham K. Valekunja Sandipan Ray Mathieu Nollet Akhilesh B. Reddy Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleep Communications Biology |
| title | Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleep |
| title_full | Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleep |
| title_fullStr | Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleep |
| title_full_unstemmed | Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleep |
| title_short | Single-cell transcriptomics and cell-specific proteomics reveals molecular signatures of sleep |
| title_sort | single cell transcriptomics and cell specific proteomics reveals molecular signatures of sleep |
| url | https://doi.org/10.1038/s42003-022-03800-3 |
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