Management of paediatric ectopia lentis at an Indonesian referral hospital: A retrospective review

Background: Ectopia lentis in children is rare and often associated with systemic conditions. Left untreated, it can lead to visually debilitating complications. Although there are various techniques available, no current consensus for treatment of paediatric ectopia lentis exists. Aim: To describe...

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Main Authors: Julie D. Barliana, Dian E. Yulia, Diajeng A. Soeharto
Format: Article
Language:English
Published: AOSIS 2022-07-01
Series:African Vision and Eye Health
Subjects:
Online Access:https://avehjournal.org/index.php/aveh/article/view/768
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author Julie D. Barliana
Dian E. Yulia
Diajeng A. Soeharto
author_facet Julie D. Barliana
Dian E. Yulia
Diajeng A. Soeharto
author_sort Julie D. Barliana
collection DOAJ
description Background: Ectopia lentis in children is rare and often associated with systemic conditions. Left untreated, it can lead to visually debilitating complications. Although there are various techniques available, no current consensus for treatment of paediatric ectopia lentis exists. Aim: To describe the management and visual outcomes of paediatric ectopia lentis in an academic referral hospital. Setting: This study was conducted at Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia. Methods: A retrospective review was conducted on the medical records of all paediatric ectopia lentis patients treated at our hospital, from 2011 to 2020. Primary outcomes include uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), treatment, surgical technique, selection of intraocular lens (IOL), and postoperative complications. Results: This study included 66 eyes of 39 patients. Average age at initial presentation was 7.8 (2–17) years. Aetiology was mostly non-traumatic, whilst four were secondary to trauma. All eyes except one underwent surgery, and IOLs were inserted in 57.4% of the non-traumatic cohort, with iris-claw IOL as the most popular choice (85.7%). Uncorrected visual acuity and BCVA significantly improved in pseudophakic and aphakic groups (p  0.05). Nearly 60% achieved a BCVA of 6/12 or greater, and the proportion was higher amongst pseudophakic group. Ten eyes had post-operative complications, with a median onset of 393 (1–1095) days after surgery. Conclusion: With varied techniques used to manage paediatric ectopia lentis, the choice of technique was dependent on individual patient condition and surgeon preference. Whilst the proportion of eyes with BCVA of ≥ 6/12 was higher amongst the pseudophakic eyes than aphakic eyes, IOL implantation entails the risk of complications, whereas no complications occurred in those left aphakic. Therefore, no particular technique can be considered marginally superior to the other, and larger studies are needed.
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spelling doaj.art-573a52d4d7be4395b272a6fcb7cc81432022-12-22T03:41:26ZengAOSISAfrican Vision and Eye Health2413-31832410-15162022-07-01811e1e610.4102/aveh.v81i1.768514Management of paediatric ectopia lentis at an Indonesian referral hospital: A retrospective reviewJulie D. Barliana0Dian E. Yulia1Diajeng A. Soeharto2Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National Central Hospital, JakartaDepartment of Ophthalmology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National Central Hospital, JakartaDepartment of Ophthalmology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National Central Hospital, JakartaBackground: Ectopia lentis in children is rare and often associated with systemic conditions. Left untreated, it can lead to visually debilitating complications. Although there are various techniques available, no current consensus for treatment of paediatric ectopia lentis exists. Aim: To describe the management and visual outcomes of paediatric ectopia lentis in an academic referral hospital. Setting: This study was conducted at Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia. Methods: A retrospective review was conducted on the medical records of all paediatric ectopia lentis patients treated at our hospital, from 2011 to 2020. Primary outcomes include uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), treatment, surgical technique, selection of intraocular lens (IOL), and postoperative complications. Results: This study included 66 eyes of 39 patients. Average age at initial presentation was 7.8 (2–17) years. Aetiology was mostly non-traumatic, whilst four were secondary to trauma. All eyes except one underwent surgery, and IOLs were inserted in 57.4% of the non-traumatic cohort, with iris-claw IOL as the most popular choice (85.7%). Uncorrected visual acuity and BCVA significantly improved in pseudophakic and aphakic groups (p  0.05). Nearly 60% achieved a BCVA of 6/12 or greater, and the proportion was higher amongst pseudophakic group. Ten eyes had post-operative complications, with a median onset of 393 (1–1095) days after surgery. Conclusion: With varied techniques used to manage paediatric ectopia lentis, the choice of technique was dependent on individual patient condition and surgeon preference. Whilst the proportion of eyes with BCVA of ≥ 6/12 was higher amongst the pseudophakic eyes than aphakic eyes, IOL implantation entails the risk of complications, whereas no complications occurred in those left aphakic. Therefore, no particular technique can be considered marginally superior to the other, and larger studies are needed.https://avehjournal.org/index.php/aveh/article/view/768ectopia lentischildrenpseudophakiaiolophthalmic surgery
spellingShingle Julie D. Barliana
Dian E. Yulia
Diajeng A. Soeharto
Management of paediatric ectopia lentis at an Indonesian referral hospital: A retrospective review
African Vision and Eye Health
ectopia lentis
children
pseudophakia
iol
ophthalmic surgery
title Management of paediatric ectopia lentis at an Indonesian referral hospital: A retrospective review
title_full Management of paediatric ectopia lentis at an Indonesian referral hospital: A retrospective review
title_fullStr Management of paediatric ectopia lentis at an Indonesian referral hospital: A retrospective review
title_full_unstemmed Management of paediatric ectopia lentis at an Indonesian referral hospital: A retrospective review
title_short Management of paediatric ectopia lentis at an Indonesian referral hospital: A retrospective review
title_sort management of paediatric ectopia lentis at an indonesian referral hospital a retrospective review
topic ectopia lentis
children
pseudophakia
iol
ophthalmic surgery
url https://avehjournal.org/index.php/aveh/article/view/768
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