Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans

Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans

The mechanisms underlying biological aging are becoming recognized as therapeutic targets to delay the onset of multiple age-related morbidities. Even greater health benefits can potentially be achieved by halting or reversing age-associated changes. C. elegans restore their tissues and normal longe...

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Bibliographic Details
Main Authors: Nikolay Burnaevskiy, Shengying Chen, Miguel Mailig, Anthony Reynolds, Shruti Karanth, Alexander Mendenhall, Marc Van Gilst, Matt Kaeberlein
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
diapause
starvation
rejuvenation
ribosomal RNA
FUDR
germline stem cells
Online Access:https://elifesciences.org/articles/36194

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