UCseek: ultrasensitive early detection and recurrence monitoring of urothelial carcinoma by shallow-depth genome-wide bisulfite sequencing of urinary sediment DNAResearch in context

UCseek: ultrasensitive early detection and recurrence monitoring of urothelial carcinoma by shallow-depth genome-wide bisulfite sequencing of urinary sediment DNAResearch in context

Summary: Background: Current methods for the detection and surveillance of urothelial carcinomas (UCs) are often invasive, costly, and not effective for low-grade, early-stage, and minimal residual disease (MRD) tumors. We aimed to develop and validate a model from urine sediments to predict differ...

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Bibliographic Details
Main Authors: Ping Wang, Yue Shi, Jianye Zhang, Jianzhong Shou, Mingxin Zhang, Daojia Zou, Yuan Liang, Juan Li, Yezhen Tan, Mei Zhang, Xingang Bi, Liqun Zhou, Weimin Ci, Xuesong Li
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:EBioMedicine
Subjects:
Urothelial carcinoma
Molecular diagnostics
Tumor markers
Diagnosis
Relapse monitoring
Machine learning
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423000026

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http://www.sciencedirect.com/science/article/pii/S2352396423000026

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