Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)
Objective: Gastritis represent one of more disease in clinic, on 2001 prevalention of cronic gastritis in Indonesia 4.3% of 100.000 population and caused additive like formaldehyde. Formaldehyde was misused especially in food industry, if consumed can cause organ’s disparity. Intention of this resea...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universitas Muhammadiyah Semarang
2016-05-01
|
| Series: | Magna Medika |
| Subjects: | |
| Online Access: | https://jurnal.unimus.ac.id/index.php/APKKM/article/view/1933 |
| _version_ | 1819013110459006976 |
|---|---|
| author | Muhammad Fadhol Romdhoni |
| author_facet | Muhammad Fadhol Romdhoni |
| author_sort | Muhammad Fadhol Romdhoni |
| collection | DOAJ |
| description | Objective: Gastritis represent one of more disease in clinic, on 2001 prevalention of cronic gastritis in Indonesia 4.3% of 100.000 population and caused additive like formaldehyde. Formaldehyde was misused especially in food industry, if consumed can cause organ’s disparity. Intention of this research is prove the Effect of Formaldehyde peroral subacute on the stomach mucosal of White Rat Strain Wistar (Rattus Norvegicus strain wistar)Method & Materials: The design of the study was pure experimental which usingThe Posttest Control Group Design. Sample were white mice which divided into 4 groups. Group I is as a control, without formaldehyde, and another groups were given with formaldehyde doses 20 ppm, 40 ppm, and 80 ppm. Result and discussion: The results should that formaldehyde can cause hyperplasia, hypertrophic, atopic, chafe (ANOVA p=0.000). The mechanism of action possibility as DNA cross-linked by protein than gene expression anormal.Conclusions: The study concluded that formaldehyde can cause hyperplasia, hypertrophic, atopic, and chafe on the mucosal stomach of white rat strain wistar and further study was needed to know minimum doses than can change of stomach mucosal and than mecahanism of action about them. |
| first_indexed | 2024-12-21T01:54:44Z |
| format | Article |
| id | doaj.art-5748fdbd92c147da836ec55b71a2376c |
| institution | Directory Open Access Journal |
| issn | 2407-0505 2774-2318 |
| language | English |
| last_indexed | 2024-12-21T01:54:44Z |
| publishDate | 2016-05-01 |
| publisher | Universitas Muhammadiyah Semarang |
| record_format | Article |
| series | Magna Medika |
| spelling | doaj.art-5748fdbd92c147da836ec55b71a2376c2022-12-21T19:19:49ZengUniversitas Muhammadiyah SemarangMagna Medika2407-05052774-23182016-05-011216216910.26714/magnamed.1.2.2015.162-1691905Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar)Muhammad Fadhol Romdhoni0FK UMPurwokerto, PurwokertoObjective: Gastritis represent one of more disease in clinic, on 2001 prevalention of cronic gastritis in Indonesia 4.3% of 100.000 population and caused additive like formaldehyde. Formaldehyde was misused especially in food industry, if consumed can cause organ’s disparity. Intention of this research is prove the Effect of Formaldehyde peroral subacute on the stomach mucosal of White Rat Strain Wistar (Rattus Norvegicus strain wistar)Method & Materials: The design of the study was pure experimental which usingThe Posttest Control Group Design. Sample were white mice which divided into 4 groups. Group I is as a control, without formaldehyde, and another groups were given with formaldehyde doses 20 ppm, 40 ppm, and 80 ppm. Result and discussion: The results should that formaldehyde can cause hyperplasia, hypertrophic, atopic, chafe (ANOVA p=0.000). The mechanism of action possibility as DNA cross-linked by protein than gene expression anormal.Conclusions: The study concluded that formaldehyde can cause hyperplasia, hypertrophic, atopic, and chafe on the mucosal stomach of white rat strain wistar and further study was needed to know minimum doses than can change of stomach mucosal and than mecahanism of action about them.https://jurnal.unimus.ac.id/index.php/APKKM/article/view/1933gastritisformaldehydestomach mucosalrat |
| spellingShingle | Muhammad Fadhol Romdhoni Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar) Magna Medika gastritis formaldehyde stomach mucosal rat |
| title | Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar) |
| title_full | Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar) |
| title_fullStr | Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar) |
| title_full_unstemmed | Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar) |
| title_short | Pengaruh Pemberian Formalin Peroral Terhadap Mukosa Lambung Tikus Putih Strain Wistar (Rattus Norvegicus Strain Wistar) |
| title_sort | pengaruh pemberian formalin peroral terhadap mukosa lambung tikus putih strain wistar rattus norvegicus strain wistar |
| topic | gastritis formaldehyde stomach mucosal rat |
| url | https://jurnal.unimus.ac.id/index.php/APKKM/article/view/1933 |
| work_keys_str_mv | AT muhammadfadholromdhoni pengaruhpemberianformalinperoralterhadapmukosalambungtikusputihstrainwistarrattusnorvegicusstrainwistar |