Epigenetic Role of Histone Lysine Methyltransferase and Demethylase on the Expression of Transcription Factors Associated with the Epithelial-to-Mesenchymal Transition of Lung Adenocarcinoma Metastasis to the Brain

Epigenetic Role of Histone Lysine Methyltransferase and Demethylase on the Expression of Transcription Factors Associated with the Epithelial-to-Mesenchymal Transition of Lung Adenocarcinoma Metastasis to the Brain

Purpose: The objective of this study was to investigate the epigenetic role of histone lysine methylation/demethylation on the expression of epithelial-to-mesenchymal transition (EMT) associated transcriptional factors (TFs) during the metastasis of lung adenocarcinoma to the brain. Methods: Paired...

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Bibliographic Details
Main Authors: Young Min Lee, Seok Hyun Kim, Minseok S. Kim, Dae Cheol Kim, Eun Hee Lee, Ju Suk Lee, Sung-Hun Lee, Young Zoon Kim
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
lung cancer
brain metastasis
epigenome
histone modification
epithelial-to-mesenchymal transition
Online Access:https://www.mdpi.com/2072-6694/12/12/3632

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