Redox–Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy

Redox–Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy

In this study, we examined the effect of six months of positive airway pressure (PAP) therapy on Obstructive Sleep Apnea (OSA) red blood cell (RBC) proteome by two dimensional difference gel electrophoresis (2D-DIGE) - based proteomics followed by Western blotting (WB) validation. The discovered dys...

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Bibliographic Details
Main Authors:	Cristina Valentim-Coelho, Fátima Vaz, Marília Antunes, Sofia Neves, Inês L. Martins, Hugo Osório, Amélia Feliciano, Paula Pinto, Cristina Bárbara, Deborah Penque
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Series:	Antioxidants
Subjects:	obstructive sleep apnea (OSA) positive airway pressure (PAP) peroxiredoxin-2 (PRDX2) glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Cys-sulfinylation/Cys-sulfonylation proteomics-biomarkers
Online Access:	https://www.mdpi.com/2076-3921/9/12/1184

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