Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs
In the present work, the development of a method based on the coupling of flow analysis (FA), hydride generation (HG), and derivative molecular absorption spectrophotometry (D-EAM) in gas phase (GP), is described in order to determine total antimony in antileishmanial products. Second derivative ord...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Química
2009-01-01
|
| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000200013 |
| _version_ | 1811197227166597120 |
|---|---|
| author | Máximo Gallignani María del Rosario Brunetto Fernando Ovalles |
| author_facet | Máximo Gallignani María del Rosario Brunetto Fernando Ovalles |
| author_sort | Máximo Gallignani |
| collection | DOAJ |
| description | In the present work, the development of a method based on the coupling of flow analysis (FA), hydride generation (HG), and derivative molecular absorption spectrophotometry (D-EAM) in gas phase (GP), is described in order to determine total antimony in antileishmanial products. Second derivative order (D²224nm) of the absorption spectrum (190 - 300 nm) is utilized as measurement criterion. Each one of the parameters involved in the development of the proposed method was examined and optimized. The utilization of the EAM in GP as detection system in a continuous mode instead of atomic absorption spectrometry represents the great potential of the analytic proposal. |
| first_indexed | 2024-04-12T01:10:59Z |
| format | Article |
| id | doaj.art-57592dc7079643f48b2da4816d1b30e3 |
| institution | Directory Open Access Journal |
| issn | 0100-4042 1678-7064 |
| language | English |
| last_indexed | 2024-04-12T01:10:59Z |
| publishDate | 2009-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-57592dc7079643f48b2da4816d1b30e32022-12-22T03:54:05ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642009-01-0132233734210.1590/S0100-40422009000200013Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugsMáximo GallignaniMaría del Rosario BrunettoFernando OvallesIn the present work, the development of a method based on the coupling of flow analysis (FA), hydride generation (HG), and derivative molecular absorption spectrophotometry (D-EAM) in gas phase (GP), is described in order to determine total antimony in antileishmanial products. Second derivative order (D²224nm) of the absorption spectrum (190 - 300 nm) is utilized as measurement criterion. Each one of the parameters involved in the development of the proposed method was examined and optimized. The utilization of the EAM in GP as detection system in a continuous mode instead of atomic absorption spectrometry represents the great potential of the analytic proposal.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000200013gaseous phase UV molecular absorption spectrophotometryantimonyleishmaniasis |
| spellingShingle | Máximo Gallignani María del Rosario Brunetto Fernando Ovalles Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs Química Nova gaseous phase UV molecular absorption spectrophotometry antimony leishmaniasis |
| title | Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs |
| title_full | Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs |
| title_fullStr | Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs |
| title_full_unstemmed | Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs |
| title_short | Flow analysis-hydride generation-gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs |
| title_sort | flow analysis hydride generation gas phase derivative molecular absorption spectrophotometric determination of antimony in antileishmanial drugs |
| topic | gaseous phase UV molecular absorption spectrophotometry antimony leishmaniasis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000200013 |
| work_keys_str_mv | AT maximogallignani flowanalysishydridegenerationgasphasederivativemolecularabsorptionspectrophotometricdeterminationofantimonyinantileishmanialdrugs AT mariadelrosariobrunetto flowanalysishydridegenerationgasphasederivativemolecularabsorptionspectrophotometricdeterminationofantimonyinantileishmanialdrugs AT fernandoovalles flowanalysishydridegenerationgasphasederivativemolecularabsorptionspectrophotometricdeterminationofantimonyinantileishmanialdrugs |