Safety and effectiveness of physical training in inotrop-dependent patients with compensation for chronic heart failure at the level of the III-IV functional class
Aim. To assess the safety and effectiveness of physical training in inotrop-dependent patients with stabilization of the course of chronic heart failure (CHF) at the level of the III-IV functional class (FC). Materials and methods. The prospective randomized study included men of 18-65 years old who...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Concilium Medicum
2019-09-01
|
| Series: | КардиоСоматика |
| Subjects: | |
| Online Access: | https://cardiosomatics.orscience.ru/2221-7185/article/viewFile/45918/pdf |
| _version_ | 1818600536228757504 |
|---|---|
| author | Mariia A. Bortsova Elena A. Demchenko Petr A. Fedotov Olga S. Ganenko Tatiana A. Lelyavina Viktoriia L. Galenko Sergei G. Zamesov Oksana A. Babich Mariia Yu. Sitnikova |
| author_facet | Mariia A. Bortsova Elena A. Demchenko Petr A. Fedotov Olga S. Ganenko Tatiana A. Lelyavina Viktoriia L. Galenko Sergei G. Zamesov Oksana A. Babich Mariia Yu. Sitnikova |
| author_sort | Mariia A. Bortsova |
| collection | DOAJ |
| description | Aim. To assess the safety and effectiveness of physical training in inotrop-dependent patients with stabilization of the course of chronic heart failure (CHF) at the level of the III-IV functional class (FC). Materials and methods. The prospective randomized study included men of 18-65 years old who were committed to Almazov National medical research center "due to decompensated CHF III-IV FC, left ventricular ejection fraction of 30% or less due to coronary heart disease or dilated cardiomyopathy receiving dopamine or dobutamine for 2 weeks or more, stabilizing heart failure at level III-IV FC and arterial pressure 90/60 mm Hg and above against the background of ongoing inotropic therapy. Patients were randomized into 2 groups: 1st - those participating in the physical rehabilitation program (PRP), 2nd - receiving standard CHF therapy. Results. There was no increase in the number of fatal cases and the number of patients with episodes of decompensation of CHF in the 1st group compared with the 2nd group. The number of episodes of CHF decompensation before FC IV was higher in the 2nd group compared to the 1st: 13 (50%) in the 1st group and 20 (80%) in the 2nd (p=0.04). Episodes of CHF decompensation, requiring transfer to the anesthesiology and resuscitation departments, were 2 times less frequent in patients of the 1st group compared to the 2nd: 8 (31%) and 16 (64%), respectively (p=0.03). In patients with the 1st group, malignant ventricular arrhythmias were not registered during physical training and for 3 hours after their completion. There was a tendency (without achieving a statistically significant difference) to a decrease in pulmonary thromboembolism episodes in patients of the 1st group compared with the 2nd (p=0.05). In the 1st group, after 6 months, there was a decrease in the number of lower respiratory tract infections - bronchitis + pneumonia compared with the 2nd group (p=0.0006). Conclusion. Participation of inotropic-dependent patients in individually designed RPF does not increase their mortality and does not increase their number of life-threatening cardiac rhythm disturbances. In the group of inotropic-dependent patients participating in RPF, there was a significant decrease in the number of lower respiratory tract infections and a tendency to a decrease in the number of pulmonary embolism compared with patients not participating in RPF. |
| first_indexed | 2024-12-16T12:37:03Z |
| format | Article |
| id | doaj.art-575cf8e0ad6740838d58d832437d5141 |
| institution | Directory Open Access Journal |
| issn | 2221-7185 2658-5707 |
| language | English |
| last_indexed | 2024-12-16T12:37:03Z |
| publishDate | 2019-09-01 |
| publisher | Concilium Medicum |
| record_format | Article |
| series | КардиоСоматика |
| spelling | doaj.art-575cf8e0ad6740838d58d832437d51412022-12-21T22:31:32ZengConcilium MedicumКардиоСоматика2221-71852658-57072019-09-0110361210.26442/22217185.2019.3.19044241555Safety and effectiveness of physical training in inotrop-dependent patients with compensation for chronic heart failure at the level of the III-IV functional classMariia A. Bortsova0Elena A. Demchenko1Petr A. Fedotov2Olga S. Ganenko3Tatiana A. Lelyavina4Viktoriia L. Galenko5Sergei G. Zamesov6Oksana A. Babich7Mariia Yu. Sitnikova8Almazov National Medical Research CenterAlmazov National Medical Research CenterAlmazov National Medical Research CenterAlmazov National Medical Research CenterAlmazov National Medical Research CenterAlmazov National Medical Research CenterCity Hospital №26Almazov National Medical Research CenterAlmazov National Medical Research CenterAim. To assess the safety and effectiveness of physical training in inotrop-dependent patients with stabilization of the course of chronic heart failure (CHF) at the level of the III-IV functional class (FC). Materials and methods. The prospective randomized study included men of 18-65 years old who were committed to Almazov National medical research center "due to decompensated CHF III-IV FC, left ventricular ejection fraction of 30% or less due to coronary heart disease or dilated cardiomyopathy receiving dopamine or dobutamine for 2 weeks or more, stabilizing heart failure at level III-IV FC and arterial pressure 90/60 mm Hg and above against the background of ongoing inotropic therapy. Patients were randomized into 2 groups: 1st - those participating in the physical rehabilitation program (PRP), 2nd - receiving standard CHF therapy. Results. There was no increase in the number of fatal cases and the number of patients with episodes of decompensation of CHF in the 1st group compared with the 2nd group. The number of episodes of CHF decompensation before FC IV was higher in the 2nd group compared to the 1st: 13 (50%) in the 1st group and 20 (80%) in the 2nd (p=0.04). Episodes of CHF decompensation, requiring transfer to the anesthesiology and resuscitation departments, were 2 times less frequent in patients of the 1st group compared to the 2nd: 8 (31%) and 16 (64%), respectively (p=0.03). In patients with the 1st group, malignant ventricular arrhythmias were not registered during physical training and for 3 hours after their completion. There was a tendency (without achieving a statistically significant difference) to a decrease in pulmonary thromboembolism episodes in patients of the 1st group compared with the 2nd (p=0.05). In the 1st group, after 6 months, there was a decrease in the number of lower respiratory tract infections - bronchitis + pneumonia compared with the 2nd group (p=0.0006). Conclusion. Participation of inotropic-dependent patients in individually designed RPF does not increase their mortality and does not increase their number of life-threatening cardiac rhythm disturbances. In the group of inotropic-dependent patients participating in RPF, there was a significant decrease in the number of lower respiratory tract infections and a tendency to a decrease in the number of pulmonary embolism compared with patients not participating in RPF.https://cardiosomatics.orscience.ru/2221-7185/article/viewFile/45918/pdfхроническая сердечная недостаточностьинотропная поддержкадопаминдобутаминфизическая реабилитацияфизические тренировки |
| spellingShingle | Mariia A. Bortsova Elena A. Demchenko Petr A. Fedotov Olga S. Ganenko Tatiana A. Lelyavina Viktoriia L. Galenko Sergei G. Zamesov Oksana A. Babich Mariia Yu. Sitnikova Safety and effectiveness of physical training in inotrop-dependent patients with compensation for chronic heart failure at the level of the III-IV functional class КардиоСоматика хроническая сердечная недостаточность инотропная поддержка допамин добутамин физическая реабилитация физические тренировки |
| title | Safety and effectiveness of physical training in inotrop-dependent patients with compensation for chronic heart failure at the level of the III-IV functional class |
| title_full | Safety and effectiveness of physical training in inotrop-dependent patients with compensation for chronic heart failure at the level of the III-IV functional class |
| title_fullStr | Safety and effectiveness of physical training in inotrop-dependent patients with compensation for chronic heart failure at the level of the III-IV functional class |
| title_full_unstemmed | Safety and effectiveness of physical training in inotrop-dependent patients with compensation for chronic heart failure at the level of the III-IV functional class |
| title_short | Safety and effectiveness of physical training in inotrop-dependent patients with compensation for chronic heart failure at the level of the III-IV functional class |
| title_sort | safety and effectiveness of physical training in inotrop dependent patients with compensation for chronic heart failure at the level of the iii iv functional class |
| topic | хроническая сердечная недостаточность инотропная поддержка допамин добутамин физическая реабилитация физические тренировки |
| url | https://cardiosomatics.orscience.ru/2221-7185/article/viewFile/45918/pdf |
| work_keys_str_mv | AT mariiaabortsova safetyandeffectivenessofphysicaltrainingininotropdependentpatientswithcompensationforchronicheartfailureattheleveloftheiiiivfunctionalclass AT elenaademchenko safetyandeffectivenessofphysicaltrainingininotropdependentpatientswithcompensationforchronicheartfailureattheleveloftheiiiivfunctionalclass AT petrafedotov safetyandeffectivenessofphysicaltrainingininotropdependentpatientswithcompensationforchronicheartfailureattheleveloftheiiiivfunctionalclass AT olgasganenko safetyandeffectivenessofphysicaltrainingininotropdependentpatientswithcompensationforchronicheartfailureattheleveloftheiiiivfunctionalclass AT tatianaalelyavina safetyandeffectivenessofphysicaltrainingininotropdependentpatientswithcompensationforchronicheartfailureattheleveloftheiiiivfunctionalclass AT viktoriialgalenko safetyandeffectivenessofphysicaltrainingininotropdependentpatientswithcompensationforchronicheartfailureattheleveloftheiiiivfunctionalclass AT sergeigzamesov safetyandeffectivenessofphysicaltrainingininotropdependentpatientswithcompensationforchronicheartfailureattheleveloftheiiiivfunctionalclass AT oksanaababich safetyandeffectivenessofphysicaltrainingininotropdependentpatientswithcompensationforchronicheartfailureattheleveloftheiiiivfunctionalclass AT mariiayusitnikova safetyandeffectivenessofphysicaltrainingininotropdependentpatientswithcompensationforchronicheartfailureattheleveloftheiiiivfunctionalclass |