Rapid detection of respiratory syncytial virus in community-acquired lower respiratory tract infections in children by chromatographic assay
Respiratory syncytial virus (RSV) is the single most important viral agent causing pediatric lower respiratory tract infections (LRTIs) worldwide. To evaluate the role of RSV in pediatric LRTIs, we studied 85 children <2 years of age hospitalized for community-acquired LRTIs. Nasopharyngeal aspir...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=2;spage=236;epage=260;aulast=Kumar |
| _version_ | 1819266662022512640 |
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| author | Surinder Kumar Bhanu Mehra Gulshan Rai Sethi Sanjeev R Saigal |
| author_facet | Surinder Kumar Bhanu Mehra Gulshan Rai Sethi Sanjeev R Saigal |
| author_sort | Surinder Kumar |
| collection | DOAJ |
| description | Respiratory syncytial virus (RSV) is the single most important viral agent causing pediatric lower respiratory tract infections (LRTIs) worldwide. To evaluate the role of RSV in pediatric LRTIs, we studied 85 children <2 years of age hospitalized for community-acquired LRTIs. Nasopharyngeal aspirates were obtained on admission for the detection of RSV antigen by immunochromatographic assay. Demographic, clinical, and radiological findings for RSV antigen were compared. Data analysis was performed by Chi-square test. A relatively higher number of RSV-infected children 32 (60.4%) were below 6 months of age. Clinical and radiological findings in both RSV-positive and RSV-negative groups were comparable. RSV antigen was positive in 53 (62.4%) with immunochromatography. Our study confirms that RSV plays a significant role in community-acquired LRTIs in children. |
| first_indexed | 2024-12-23T21:04:50Z |
| format | Article |
| id | doaj.art-575d9fd187b94e5cb00b6ddc0241a13e |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-23T21:04:50Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-575d9fd187b94e5cb00b6ddc0241a13e2022-12-21T17:31:15ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292018-01-0161223626010.4103/IJPM.IJPM_789_16Rapid detection of respiratory syncytial virus in community-acquired lower respiratory tract infections in children by chromatographic assaySurinder KumarBhanu MehraGulshan Rai SethiSanjeev R SaigalRespiratory syncytial virus (RSV) is the single most important viral agent causing pediatric lower respiratory tract infections (LRTIs) worldwide. To evaluate the role of RSV in pediatric LRTIs, we studied 85 children <2 years of age hospitalized for community-acquired LRTIs. Nasopharyngeal aspirates were obtained on admission for the detection of RSV antigen by immunochromatographic assay. Demographic, clinical, and radiological findings for RSV antigen were compared. Data analysis was performed by Chi-square test. A relatively higher number of RSV-infected children 32 (60.4%) were below 6 months of age. Clinical and radiological findings in both RSV-positive and RSV-negative groups were comparable. RSV antigen was positive in 53 (62.4%) with immunochromatography. Our study confirms that RSV plays a significant role in community-acquired LRTIs in children.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=2;spage=236;epage=260;aulast=KumarChromatographic immunoassaylower respiratory tract infectionsrespiratory syncytial virus |
| spellingShingle | Surinder Kumar Bhanu Mehra Gulshan Rai Sethi Sanjeev R Saigal Rapid detection of respiratory syncytial virus in community-acquired lower respiratory tract infections in children by chromatographic assay Indian Journal of Pathology and Microbiology Chromatographic immunoassay lower respiratory tract infections respiratory syncytial virus |
| title | Rapid detection of respiratory syncytial virus in community-acquired lower respiratory tract infections in children by chromatographic assay |
| title_full | Rapid detection of respiratory syncytial virus in community-acquired lower respiratory tract infections in children by chromatographic assay |
| title_fullStr | Rapid detection of respiratory syncytial virus in community-acquired lower respiratory tract infections in children by chromatographic assay |
| title_full_unstemmed | Rapid detection of respiratory syncytial virus in community-acquired lower respiratory tract infections in children by chromatographic assay |
| title_short | Rapid detection of respiratory syncytial virus in community-acquired lower respiratory tract infections in children by chromatographic assay |
| title_sort | rapid detection of respiratory syncytial virus in community acquired lower respiratory tract infections in children by chromatographic assay |
| topic | Chromatographic immunoassay lower respiratory tract infections respiratory syncytial virus |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2018;volume=61;issue=2;spage=236;epage=260;aulast=Kumar |
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