Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer

Intravesical immunotherapy with attenuated strains of Mycobacterium bovis is a widely used therapeutic option in patients with non-muscle-invasive transitional cell carcinoma of the bladder. A rare complication of intravesical therapy with the Bacillus Calmette-Guérin vaccine is granulomatous pro...

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Main Authors: Waldemar Białek, Sławomir Rudzki, Paweł Iberszer, Lech Wronecki
Format: Article
Language:English
Published: Sciendo 2016-12-01
Series:Journal of Ultrasonography
Subjects:
Online Access:http://jultrason.pl/index.php/issues/volume-16-no-67/granulomatous-prostatitis-after-intravesical-immunotherapy-mimicking-prostate-cancer?aid=485
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author Waldemar Białek
Sławomir Rudzki
Paweł Iberszer
Lech Wronecki
author_facet Waldemar Białek
Sławomir Rudzki
Paweł Iberszer
Lech Wronecki
author_sort Waldemar Białek
collection DOAJ
description Intravesical immunotherapy with attenuated strains of Mycobacterium bovis is a widely used therapeutic option in patients with non-muscle-invasive transitional cell carcinoma of the bladder. A rare complication of intravesical therapy with the Bacillus Calmette-Guérin vaccine is granulomatous prostatitis, which due to increasing levels of prostate-specific antigen and abnormalities found in transrectal examination of the prostate may suggest concomitant prostate cancer. A case of extensive granulomatous prostatitis in a 61-year-old patient which occurred after the first course of a well-tolerated Bacillus Calmette-Guérin therapy is presented. Due to abnormalities found in rectal examination and an abnormal transrectal ultrasound image of the prostate with extensive infiltration mimicking neoplastic hyperplasia a core biopsy of the prostate was performed. Histopathological examination revealed inflammatory infiltration sites of tuberculosis origin.
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spelling doaj.art-575dd3f25b9c43b5aa184e04e27920b92022-12-22T02:06:09ZengSciendoJournal of Ultrasonography2084-84042451-070X2016-12-01166740441010.15557/JoU.2016.0040Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancerWaldemar Białek0Sławomir Rudzki1Paweł Iberszer2Lech Wronecki3Department of Urology, 1st Military Hospital, Lublin, Poland; Department of General and Transplant Surgery and Nutritional Treatment, Medical University of Lublin, PolandDepartment of General and Transplant Surgery and Nutritional Treatment, Medical University of Lublin, PolandDepartment of Urology, Railway Hospital in Lublin, PolandDepartment of Clinical Pathomorphology, Medical University of Lublin, PolandIntravesical immunotherapy with attenuated strains of Mycobacterium bovis is a widely used therapeutic option in patients with non-muscle-invasive transitional cell carcinoma of the bladder. A rare complication of intravesical therapy with the Bacillus Calmette-Guérin vaccine is granulomatous prostatitis, which due to increasing levels of prostate-specific antigen and abnormalities found in transrectal examination of the prostate may suggest concomitant prostate cancer. A case of extensive granulomatous prostatitis in a 61-year-old patient which occurred after the first course of a well-tolerated Bacillus Calmette-Guérin therapy is presented. Due to abnormalities found in rectal examination and an abnormal transrectal ultrasound image of the prostate with extensive infiltration mimicking neoplastic hyperplasia a core biopsy of the prostate was performed. Histopathological examination revealed inflammatory infiltration sites of tuberculosis origin.http://jultrason.pl/index.php/issues/volume-16-no-67/granulomatous-prostatitis-after-intravesical-immunotherapy-mimicking-prostate-cancer?aid=485granulomatous prostatitisprostate biopsytransrectal ultrasound
spellingShingle Waldemar Białek
Sławomir Rudzki
Paweł Iberszer
Lech Wronecki
Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer
Journal of Ultrasonography
granulomatous prostatitis
prostate biopsy
transrectal ultrasound
title Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer
title_full Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer
title_fullStr Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer
title_full_unstemmed Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer
title_short Granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer
title_sort granulomatous prostatitis after intravesical immunotherapy mimicking prostate cancer
topic granulomatous prostatitis
prostate biopsy
transrectal ultrasound
url http://jultrason.pl/index.php/issues/volume-16-no-67/granulomatous-prostatitis-after-intravesical-immunotherapy-mimicking-prostate-cancer?aid=485
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AT sławomirrudzki granulomatousprostatitisafterintravesicalimmunotherapymimickingprostatecancer
AT pawełiberszer granulomatousprostatitisafterintravesicalimmunotherapymimickingprostatecancer
AT lechwronecki granulomatousprostatitisafterintravesicalimmunotherapymimickingprostatecancer