| Summary: | Skin is the largest organ of our body and it protects interior organs
against several environmental factors. Hyperpigmentation problem occurs as a
result of abnormal melanin accumulation in the skin. A considerable amount of
world’s population uses skin whitening products. It is known that various algae-derived secondary metabolites play an
important role in skin problems. Therefore, the tyrosinase inhibitory
activities of S. obliquus ethanol and
water extracts were evaluated in the present study. Tyrosinase activity was
determined spectrophotometrically at 492 nm. The ethanol extract showed the
higher inhibitory activity on tyrosinase enzyme (IC50: 0.0270 g/mL) than water extract (IC50:
0.2882 g/mL). This
result may have stemmed from the vanillic, ferulic acid and rutin components that were
identified by RP-HPLC only in the ethanol extract.
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