PCDH17 gene promoter methylation status in a cohort of Egyptian women with epithelial ovarian cancer

PCDH17 gene promoter methylation status in a cohort of Egyptian women with epithelial ovarian cancer

Abstract Background and objective Ovarian cancer is a leading cause of female mortality. Epigenetic changes occur in early stages of carcinogenesis and represent a marker for cancer diagnosis. Protocadherin 17 (PCDH17) is a tumor suppressor gene involved in cell adhesion and apoptosis. The methylati...

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Bibliographic Details
Main Authors: Sherif Mohamed Elsharkawi, Dalal Elkaffash, Pacint Moez, Nour El-Etreby, Eman Sheta, Raghda Saad Zaghloul Taleb
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Cancer
Subjects:
Ovarian cancer
PCDH17
Pyrosequencing
Epigenetics
DNA methylation
Online Access:https://doi.org/10.1186/s12885-023-10549-3

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