Bacterial lysis, autophagy and innate immune responses during adjunctive phage therapy in a child

Bacterial lysis, autophagy and innate immune responses during adjunctive phage therapy in a child

Abstract Adjunctive phage therapy was used in an attempt to avoid catastrophic outcomes from extensive chronic Pseudomonas aeruginosa osteoarticular infection in a 7‐year‐old child. Monitoring of phage and bacterial kinetics allowed real‐time phage dose adjustment, and along with markers of the huma...

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Bibliographic Details
Main Authors: Ameneh Khatami, Ruby C Y Lin, Aleksandra Petrovic‐Fabijan, Sivan Alkalay‐Oren, Sulaiman Almuzam, Philip N Britton, Michael J Brownstein, Quang Dao, Joe Fackler, Ronen Hazan, Bri’Anna Horne, Ran Nir‐Paz, Jonathan R Iredell
Format: Article
Language:English
Published: Springer Nature 2021-09-01
Series:EMBO Molecular Medicine
Subjects:
bacteriophage
child
immune response
osteoarticular infection
Pseudomonas aeruginosa
Online Access:https://doi.org/10.15252/emmm.202113936

Internet

https://doi.org/10.15252/emmm.202113936

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