Hypovitaminosis D Implicated in the Development of Stress, Metabolic Syndrome and Hepatic Steatosis among Health Science Undergraduates attending a Tertiary Care Institute in Tamil Nadu, India
Introduction: Vitamin D deficiency is prevalent worldwide and its association with stress has become an emerging problem. A collection of linked physiological, biochemical, clinical, and metabolic risk factors is known as the Metabolic Syndrome (MS). High stress level is found associated with vitami...
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JCDR Research and Publications Private Limited
2023-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/17809/60452_CE[Ra1]_F(IS)_PF1(HB_SHU)_PFA(HB_KM)_PN(KM).pdf |
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| author | SK Aishwarya B Gayathri M Prabu P Renuka VM Vinodhini |
| author_facet | SK Aishwarya B Gayathri M Prabu P Renuka VM Vinodhini |
| author_sort | SK Aishwarya |
| collection | DOAJ |
| description | Introduction: Vitamin D deficiency is prevalent worldwide and its association with stress has become an emerging problem. A collection of linked physiological, biochemical, clinical, and metabolic risk factors is known as the Metabolic Syndrome (MS). High stress level is found associated with vitamin D deficiency and features of metabolic syndrome symptoms.
Aim: To estimate the prevalence of vitamin D deficiency, perceived stress, metabolic syndrome and hepatic steatosis among health science Undergraduate (UG) students and also to evaluate the association of vitamin D with percieved stress score, calcium, phosphorus, components of metabolic syndrome and indicators of liver steatosis.
Materials and Methods: This cross-sectional study was conducted in SRM Medical College, Hospital and Research Centre, Chennai, India, from February 2022 to August 2022. A total of 80 health science UG students in the age group of 19-25 years were included. The parameters included Fasting plasma glucose, Triglycerides (TGL), High Density Lipoprotein Cholesterol (HDLC), Gamma-glutamyl Transferase (GGT), phosphorus, calcium, and a Perceived Stress Scale (PSS) score scale. Data were statistically analysed using Pearson’s correlation test and Receiver Operating Characteristic (ROC) curve was used to assess the relationship of vitamin D with stress, metabolic syndrome and liver steatosis.
Results: In the present study, majority 56 (70%) had vitamin D deficiency, 23 (28.75%) had insufficiency and 1 (1.25%) had sufficiency. An estimated 6 (7.5%) of students experienced low stress, 63 (78.75%) experienced moderate stress and 11 (13.75%) experienced high perceived stress. Indicators of metabolic syndrome occurred in 13 (16.25%) of the population. Nearly 6 (7.5%) of the participants displayed manifestation of fatty liver. A negative association was found between vitamin D with stress score, Body Mass Index (BMI), waist circumference, Blood Pressure (BP), phosphorus, fasting plasma glucose, TGL, HDLC, GGT, Fatty Liver Index (FLI) score.
Conclusion: In the present study, vitamin D deficiency was most prevalent (70%), followed by metabolic syndrome, high stress and hepatic steatosis. Vitamin D showed a negative correlation with stress score, BMI, waist circumference, BP, phosphorous, fasting plasma glucose, TGL, HDLC, GGT and FLI score. |
| first_indexed | 2024-04-09T12:36:23Z |
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| id | doaj.art-5762033228b542b28bc023c6d105a9ce |
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| issn | 2249-782X 0973-709X |
| language | English |
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| publishDate | 2023-05-01 |
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| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-5762033228b542b28bc023c6d105a9ce2023-05-15T11:29:26ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-05-01175BC07BC1210.7860/JCDR/2023/60452.17809Hypovitaminosis D Implicated in the Development of Stress, Metabolic Syndrome and Hepatic Steatosis among Health Science Undergraduates attending a Tertiary Care Institute in Tamil Nadu, IndiaSK Aishwarya0B Gayathri1M Prabu2P Renuka3VM Vinodhini4Postgraduate ,Department of Biochemistry, SRM Medical College Hospital and Research Centre, SRMIST, Kattankulathur, Kanchipuram, Chennai, Tamil Nadu, India.Associate Professor, Department of Biochemistry, SRM Medical College Hospital and Research Centre, SRMIST, Kattankulathur, Kanchipuram, Chennai, Tamil Nadu, India.Tutor, Department of Biochemistry, SRM Medical College Hospital and Research Centre, SRMIST,Kattankulathur, Kanchipuram, Chennai, Tamil Nadu, India.Professor, Department of Biochemistry, SRM Medical College Hospital and Research Centre, SRMIST, Kattankulathur, Kanchipuram, Chennai, Tamil Nadu, India.Profesor and Head, Department of Biochemistry, SRM Medical College Hospital and Research Centre, SRMIST, Kattankulathur, Kanchipuram, Chennai, Tamil Nadu, India.Introduction: Vitamin D deficiency is prevalent worldwide and its association with stress has become an emerging problem. A collection of linked physiological, biochemical, clinical, and metabolic risk factors is known as the Metabolic Syndrome (MS). High stress level is found associated with vitamin D deficiency and features of metabolic syndrome symptoms. Aim: To estimate the prevalence of vitamin D deficiency, perceived stress, metabolic syndrome and hepatic steatosis among health science Undergraduate (UG) students and also to evaluate the association of vitamin D with percieved stress score, calcium, phosphorus, components of metabolic syndrome and indicators of liver steatosis. Materials and Methods: This cross-sectional study was conducted in SRM Medical College, Hospital and Research Centre, Chennai, India, from February 2022 to August 2022. A total of 80 health science UG students in the age group of 19-25 years were included. The parameters included Fasting plasma glucose, Triglycerides (TGL), High Density Lipoprotein Cholesterol (HDLC), Gamma-glutamyl Transferase (GGT), phosphorus, calcium, and a Perceived Stress Scale (PSS) score scale. Data were statistically analysed using Pearson’s correlation test and Receiver Operating Characteristic (ROC) curve was used to assess the relationship of vitamin D with stress, metabolic syndrome and liver steatosis. Results: In the present study, majority 56 (70%) had vitamin D deficiency, 23 (28.75%) had insufficiency and 1 (1.25%) had sufficiency. An estimated 6 (7.5%) of students experienced low stress, 63 (78.75%) experienced moderate stress and 11 (13.75%) experienced high perceived stress. Indicators of metabolic syndrome occurred in 13 (16.25%) of the population. Nearly 6 (7.5%) of the participants displayed manifestation of fatty liver. A negative association was found between vitamin D with stress score, Body Mass Index (BMI), waist circumference, Blood Pressure (BP), phosphorus, fasting plasma glucose, TGL, HDLC, GGT, Fatty Liver Index (FLI) score. Conclusion: In the present study, vitamin D deficiency was most prevalent (70%), followed by metabolic syndrome, high stress and hepatic steatosis. Vitamin D showed a negative correlation with stress score, BMI, waist circumference, BP, phosphorous, fasting plasma glucose, TGL, HDLC, GGT and FLI score.https://www.jcdr.net/articles/PDF/17809/60452_CE[Ra1]_F(IS)_PF1(HB_SHU)_PFA(HB_KM)_PN(KM).pdfbody mass indexfatty liverstress scorevitamin d |
| spellingShingle | SK Aishwarya B Gayathri M Prabu P Renuka VM Vinodhini Hypovitaminosis D Implicated in the Development of Stress, Metabolic Syndrome and Hepatic Steatosis among Health Science Undergraduates attending a Tertiary Care Institute in Tamil Nadu, India Journal of Clinical and Diagnostic Research body mass index fatty liver stress score vitamin d |
| title | Hypovitaminosis D Implicated in the Development of Stress, Metabolic Syndrome and Hepatic Steatosis among Health Science Undergraduates attending a Tertiary Care Institute in Tamil Nadu, India |
| title_full | Hypovitaminosis D Implicated in the Development of Stress, Metabolic Syndrome and Hepatic Steatosis among Health Science Undergraduates attending a Tertiary Care Institute in Tamil Nadu, India |
| title_fullStr | Hypovitaminosis D Implicated in the Development of Stress, Metabolic Syndrome and Hepatic Steatosis among Health Science Undergraduates attending a Tertiary Care Institute in Tamil Nadu, India |
| title_full_unstemmed | Hypovitaminosis D Implicated in the Development of Stress, Metabolic Syndrome and Hepatic Steatosis among Health Science Undergraduates attending a Tertiary Care Institute in Tamil Nadu, India |
| title_short | Hypovitaminosis D Implicated in the Development of Stress, Metabolic Syndrome and Hepatic Steatosis among Health Science Undergraduates attending a Tertiary Care Institute in Tamil Nadu, India |
| title_sort | hypovitaminosis d implicated in the development of stress metabolic syndrome and hepatic steatosis among health science undergraduates attending a tertiary care institute in tamil nadu india |
| topic | body mass index fatty liver stress score vitamin d |
| url | https://www.jcdr.net/articles/PDF/17809/60452_CE[Ra1]_F(IS)_PF1(HB_SHU)_PFA(HB_KM)_PN(KM).pdf |
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