Next Generation Sequencing of 134 Children with Autism Spectrum Disorder and Regression

Next Generation Sequencing of 134 Children with Autism Spectrum Disorder and Regression

Approximately 30% of individuals with autism spectrum disorder (ASD) experience developmental regression, the etiology of which remains largely unknown. We performed a complete literature search and identified 47 genes that had been implicated in such cases. We sequenced these genes in a preselected...

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Bibliographic Details
Main Authors: Jiani Yin, Chun-An Chun, Nikolay N. Zavadenko, Natalia L. Pechatnikova, Oxana Yu. Naumova, Harsha V. Doddapaneni, Jianhong Hu, Donna M. Muzny, Christian P. Schaaf, Elena L. Grigorenko
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Genes
Subjects:
autism
developmental regression
exon capture and sequencing
variant classification
ACMG standards and guidelines
Online Access:https://www.mdpi.com/2073-4425/11/8/853

Internet

https://www.mdpi.com/2073-4425/11/8/853

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