The effects of mifepristone on the structure of human decidua and chorion and Bax and Bcl-2 expression at early stage of pregnancy

The effects of mifepristone on the structure of human decidua and chorion and Bax and Bcl-2 expression at early stage of pregnancy

Abstract Background As a progesterone receptor antagonist, mifepristone combined with misoprostol is widely used to terminate early pregnancy in clinical practice. It has also been reported that mifepristone may cause cell death in decidual cells and result in hemorrhage of the decidua and insuffici...

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Bibliographic Details
Main Authors: Fei Tian, Hua Han, Ligang Jia, Junqin Zhang, Zhaoping Chu, Jie Li, Yuan Zhang, Ping Yan
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Pharmacology and Toxicology
Subjects:
Mifepristone
Decidua and chorion
Histology
Pregnancy
Apoptosis
Online Access:https://doi.org/10.1186/s40360-022-00592-4

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