Identification of the Repressive Domain of the Negative Circadian Clock Component CHRONO

Identification of the Repressive Domain of the Negative Circadian Clock Component CHRONO

Circadian rhythm is an endogenous, self-sustainable oscillation that participates in regulating organisms’ physiological activities. Key to this oscillation is a negative feedback by the main clock components Periods and Cryptochromes that repress the transcriptional activity of BMAL1/CLOCK (defined...

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Bibliographic Details
Main Authors:	Yu Yang, Ning Li, Jiameng Qiu, Honghua Ge, Ximing Qin
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	International Journal of Molecular Sciences
Subjects:	circadian rhythm CHRONO repression BMAL1 TTFL CRISPR/Cas9
Online Access:	https://www.mdpi.com/1422-0067/21/7/2469

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