Exclusive Enteral Nutrition in Adult Crohn’s Disease: an Overview of Clinical Practice and Perceived Barriers
Roberto de Sire, Olga Maria Nardone, Anna Testa, Giulio Calabrese, Anna Caiazzo, Fabiana Castiglione Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, ItalyCorrespondence: Fabiana CastiglioneDepartment of Clinical Medicine and Surgery, University Federico II of N...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-12-01
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| Series: | Clinical and Experimental Gastroenterology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/exclusive-enteral-nutrition-in-adult-crohns-disease-an-overview-of-cli-peer-reviewed-fulltext-article-CEG |
| _version_ | 1819007480673337344 |
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| author | de Sire R Nardone OM Testa A Calabrese G Caiazzo A Castiglione F |
| author_facet | de Sire R Nardone OM Testa A Calabrese G Caiazzo A Castiglione F |
| author_sort | de Sire R |
| collection | DOAJ |
| description | Roberto de Sire, Olga Maria Nardone, Anna Testa, Giulio Calabrese, Anna Caiazzo, Fabiana Castiglione Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, ItalyCorrespondence: Fabiana CastiglioneDepartment of Clinical Medicine and Surgery, University Federico II of Naples, Via S. Pansini 5, Naples, 80131, ItalyEmail fabcasti@unina.itAbstract: Recently, the role of nutrition in the management of Crohn’s disease (CD) is of increasing interest and the exploration of novel nutritional interventions to improve long-term management of the disease is challenging. So far, the majority of the studies on the role of exclusive enteral nutrition (EEN) in CD are conducted in the pediatric population and have highlighted the efficacy of EEN for achieving mucosal healing. This implicates that a similar approach would be beneficial in adult patients. However, the evidence for EEN in adults is heterogeneous, with meta-analyses reporting it as inferior to steroids while growing data demonstrate improvement in complicated CD. Currently, EEN is less used in adult patients with IBD. Indeed, the lack of palatability of enteral formula leads to difficulties in acceptance and compliance. The search for more tolerable and still effective diets has become an intense area of research aiming to explore the potential role of diet to control inflammation in patients with CD. Thus, this narrative review provides the state-of-the-art on the use of EEN treatment in CD and highlights the perceived barriers to its implementation in adult CD patients.Keywords: Crohn’s disease, exclusive enteral nutrition, barriers, diet, nutritional interventions |
| first_indexed | 2024-12-21T00:25:15Z |
| format | Article |
| id | doaj.art-576889b041b7439e885d0a254cb2f6e7 |
| institution | Directory Open Access Journal |
| issn | 1178-7023 |
| language | English |
| last_indexed | 2024-12-21T00:25:15Z |
| publishDate | 2021-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical and Experimental Gastroenterology |
| spelling | doaj.art-576889b041b7439e885d0a254cb2f6e72022-12-21T19:22:00ZengDove Medical PressClinical and Experimental Gastroenterology1178-70232021-12-01Volume 1449350171844Exclusive Enteral Nutrition in Adult Crohn’s Disease: an Overview of Clinical Practice and Perceived Barriersde Sire RNardone OMTesta ACalabrese GCaiazzo ACastiglione FRoberto de Sire, Olga Maria Nardone, Anna Testa, Giulio Calabrese, Anna Caiazzo, Fabiana Castiglione Department of Clinical Medicine and Surgery, University Federico II of Naples, Naples, ItalyCorrespondence: Fabiana CastiglioneDepartment of Clinical Medicine and Surgery, University Federico II of Naples, Via S. Pansini 5, Naples, 80131, ItalyEmail fabcasti@unina.itAbstract: Recently, the role of nutrition in the management of Crohn’s disease (CD) is of increasing interest and the exploration of novel nutritional interventions to improve long-term management of the disease is challenging. So far, the majority of the studies on the role of exclusive enteral nutrition (EEN) in CD are conducted in the pediatric population and have highlighted the efficacy of EEN for achieving mucosal healing. This implicates that a similar approach would be beneficial in adult patients. However, the evidence for EEN in adults is heterogeneous, with meta-analyses reporting it as inferior to steroids while growing data demonstrate improvement in complicated CD. Currently, EEN is less used in adult patients with IBD. Indeed, the lack of palatability of enteral formula leads to difficulties in acceptance and compliance. The search for more tolerable and still effective diets has become an intense area of research aiming to explore the potential role of diet to control inflammation in patients with CD. Thus, this narrative review provides the state-of-the-art on the use of EEN treatment in CD and highlights the perceived barriers to its implementation in adult CD patients.Keywords: Crohn’s disease, exclusive enteral nutrition, barriers, diet, nutritional interventionshttps://www.dovepress.com/exclusive-enteral-nutrition-in-adult-crohns-disease-an-overview-of-cli-peer-reviewed-fulltext-article-CEGcrohn’s diseaseexclusive enteral nutritionbarriersdietnutritional interventions |
| spellingShingle | de Sire R Nardone OM Testa A Calabrese G Caiazzo A Castiglione F Exclusive Enteral Nutrition in Adult Crohn’s Disease: an Overview of Clinical Practice and Perceived Barriers Clinical and Experimental Gastroenterology crohn’s disease exclusive enteral nutrition barriers diet nutritional interventions |
| title | Exclusive Enteral Nutrition in Adult Crohn’s Disease: an Overview of Clinical Practice and Perceived Barriers |
| title_full | Exclusive Enteral Nutrition in Adult Crohn’s Disease: an Overview of Clinical Practice and Perceived Barriers |
| title_fullStr | Exclusive Enteral Nutrition in Adult Crohn’s Disease: an Overview of Clinical Practice and Perceived Barriers |
| title_full_unstemmed | Exclusive Enteral Nutrition in Adult Crohn’s Disease: an Overview of Clinical Practice and Perceived Barriers |
| title_short | Exclusive Enteral Nutrition in Adult Crohn’s Disease: an Overview of Clinical Practice and Perceived Barriers |
| title_sort | exclusive enteral nutrition in adult crohn rsquo s disease an overview of clinical practice and perceived barriers |
| topic | crohn’s disease exclusive enteral nutrition barriers diet nutritional interventions |
| url | https://www.dovepress.com/exclusive-enteral-nutrition-in-adult-crohns-disease-an-overview-of-cli-peer-reviewed-fulltext-article-CEG |
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