Etoricoxib can be used for chronic nonspecific back pain: a new indication of the well-known drug

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the main class of analgesics for the relief of acute nonspecific back pain (NSBP) and for the control of chronic one (CNSBP). The choice of a NSAID is determined by the efficacy, ease of use, and safety profile of a particular drug. Etoricoxib is one...

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Main Author: A. E. Karateev
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2020-04-01
Series:Неврология, нейропсихиатрия, психосоматика
Subjects:
Online Access:https://nnp.ima-press.net/nnp/article/view/1317
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author A. E. Karateev
author_facet A. E. Karateev
author_sort A. E. Karateev
collection DOAJ
description Nonsteroidal anti-inflammatory drugs (NSAIDs) are the main class of analgesics for the relief of acute nonspecific back pain (NSBP) and for the control of chronic one (CNSBP). The choice of a NSAID is determined by the efficacy, ease of use, and safety profile of a particular drug. Etoricoxib is one of the most successful representatives of NSAIDs, which is advisable to be used in CNSBP. Double-blind, controlled studies of patients with CNSBP have indicated that etoricoxib at a dose of 60 mg/day is significantly superior to placebo and that at a dose of 150 mg/day is not inferior to diclofenac. The important advantages of etoricoxib are its good tolerance and a relatively low risk of gastrointestinal complications. The frequency of cardiovascular and renal complications with etoricoxib is not higher than those with the most popular nonselective NSAIDs. In 2020, etoricoxib was included in the number of official indications approved by the Ministry of Health of Russia for the treatment of chronic lower back pain.
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spelling doaj.art-576eaefbbdc1486ea4152cb432db4ea42023-03-13T08:42:19ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422020-04-0112212513010.14412/2074-2711-2020-2-125-130984Etoricoxib can be used for chronic nonspecific back pain: a new indication of the well-known drugA. E. Karateev0V.A. Nasonova Research Institute of RheumatologyNonsteroidal anti-inflammatory drugs (NSAIDs) are the main class of analgesics for the relief of acute nonspecific back pain (NSBP) and for the control of chronic one (CNSBP). The choice of a NSAID is determined by the efficacy, ease of use, and safety profile of a particular drug. Etoricoxib is one of the most successful representatives of NSAIDs, which is advisable to be used in CNSBP. Double-blind, controlled studies of patients with CNSBP have indicated that etoricoxib at a dose of 60 mg/day is significantly superior to placebo and that at a dose of 150 mg/day is not inferior to diclofenac. The important advantages of etoricoxib are its good tolerance and a relatively low risk of gastrointestinal complications. The frequency of cardiovascular and renal complications with etoricoxib is not higher than those with the most popular nonselective NSAIDs. In 2020, etoricoxib was included in the number of official indications approved by the Ministry of Health of Russia for the treatment of chronic lower back pain.https://nnp.ima-press.net/nnp/article/view/1317back painchronic nonspecific back painnonsteroidal anti-inflammatory drugsetoricoxibefficacysafety
spellingShingle A. E. Karateev
Etoricoxib can be used for chronic nonspecific back pain: a new indication of the well-known drug
Неврология, нейропсихиатрия, психосоматика
back pain
chronic nonspecific back pain
nonsteroidal anti-inflammatory drugs
etoricoxib
efficacy
safety
title Etoricoxib can be used for chronic nonspecific back pain: a new indication of the well-known drug
title_full Etoricoxib can be used for chronic nonspecific back pain: a new indication of the well-known drug
title_fullStr Etoricoxib can be used for chronic nonspecific back pain: a new indication of the well-known drug
title_full_unstemmed Etoricoxib can be used for chronic nonspecific back pain: a new indication of the well-known drug
title_short Etoricoxib can be used for chronic nonspecific back pain: a new indication of the well-known drug
title_sort etoricoxib can be used for chronic nonspecific back pain a new indication of the well known drug
topic back pain
chronic nonspecific back pain
nonsteroidal anti-inflammatory drugs
etoricoxib
efficacy
safety
url https://nnp.ima-press.net/nnp/article/view/1317
work_keys_str_mv AT aekarateev etoricoxibcanbeusedforchronicnonspecificbackpainanewindicationofthewellknowndrug