Granulomatosis with polyangiitis mimicking COVID‐19 pneumonia: A case report
Key Clinical Message Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a necrotizing vasculitis characterized by small‐to‐medium‐sized vessel involvement and the presence of antineutrophil cytoplasmic antibodies (ANCA). We present a case of a 26‐year‐old Asi...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-10-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.8007 |
| _version_ | 1797650411801280512 |
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| author | Arjun Basnet Sajog Kansakar Nava Raj Sharma Sudarshan Gautam Saral Lamichhane Kripa Tiwari Madalasa Pokhrel Sehajpreet Singh |
| author_facet | Arjun Basnet Sajog Kansakar Nava Raj Sharma Sudarshan Gautam Saral Lamichhane Kripa Tiwari Madalasa Pokhrel Sehajpreet Singh |
| author_sort | Arjun Basnet |
| collection | DOAJ |
| description | Key Clinical Message Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a necrotizing vasculitis characterized by small‐to‐medium‐sized vessel involvement and the presence of antineutrophil cytoplasmic antibodies (ANCA). We present a case of a 26‐year‐old Asian woman who was transferred to our center from a nearby hospital, where she presented with shortness of breath, tested positive for COVID‐19, and was being managed for COVID‐19 pneumonia. She also had hemoptysis, skin lesions, and left foot numbness. Serological markers and VATS‐guided lung biopsy confirmed the diagnosis. Treatment with methylprednisolone and rituximab led to stabilization, despite complications of subcutaneous emphysema and lower extremity neuropathic symptoms. Early recognition and appropriate management of GPA are crucial for optimal outcomes. |
| first_indexed | 2024-03-11T16:01:00Z |
| format | Article |
| id | doaj.art-5771afb8cca54993b42edca1e9d1aed1 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-11T16:01:00Z |
| publishDate | 2023-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-5771afb8cca54993b42edca1e9d1aed12023-10-25T07:12:44ZengWileyClinical Case Reports2050-09042023-10-011110n/an/a10.1002/ccr3.8007Granulomatosis with polyangiitis mimicking COVID‐19 pneumonia: A case reportArjun Basnet0Sajog Kansakar1Nava Raj Sharma2Sudarshan Gautam3Saral Lamichhane4Kripa Tiwari5Madalasa Pokhrel6Sehajpreet Singh7Maimonides Medical Center Brooklyn New York United StatesMaimonides Medical Center Brooklyn New York United StatesManipal College of Medical Sciences Pokhara NepalMaimonides Medical Center Brooklyn New York United StatesGandaki Medical College Pokhara NepalMaimonides Medical Center Brooklyn New York United StatesMontefiore New Rochelle Hospital New Rochelle New York United StatesMaimonides Medical Center Brooklyn New York United StatesKey Clinical Message Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a necrotizing vasculitis characterized by small‐to‐medium‐sized vessel involvement and the presence of antineutrophil cytoplasmic antibodies (ANCA). We present a case of a 26‐year‐old Asian woman who was transferred to our center from a nearby hospital, where she presented with shortness of breath, tested positive for COVID‐19, and was being managed for COVID‐19 pneumonia. She also had hemoptysis, skin lesions, and left foot numbness. Serological markers and VATS‐guided lung biopsy confirmed the diagnosis. Treatment with methylprednisolone and rituximab led to stabilization, despite complications of subcutaneous emphysema and lower extremity neuropathic symptoms. Early recognition and appropriate management of GPA are crucial for optimal outcomes.https://doi.org/10.1002/ccr3.8007ANCA‐associated vasculitisCOVID‐19granulomatosis with polyangiitis |
| spellingShingle | Arjun Basnet Sajog Kansakar Nava Raj Sharma Sudarshan Gautam Saral Lamichhane Kripa Tiwari Madalasa Pokhrel Sehajpreet Singh Granulomatosis with polyangiitis mimicking COVID‐19 pneumonia: A case report Clinical Case Reports ANCA‐associated vasculitis COVID‐19 granulomatosis with polyangiitis |
| title | Granulomatosis with polyangiitis mimicking COVID‐19 pneumonia: A case report |
| title_full | Granulomatosis with polyangiitis mimicking COVID‐19 pneumonia: A case report |
| title_fullStr | Granulomatosis with polyangiitis mimicking COVID‐19 pneumonia: A case report |
| title_full_unstemmed | Granulomatosis with polyangiitis mimicking COVID‐19 pneumonia: A case report |
| title_short | Granulomatosis with polyangiitis mimicking COVID‐19 pneumonia: A case report |
| title_sort | granulomatosis with polyangiitis mimicking covid 19 pneumonia a case report |
| topic | ANCA‐associated vasculitis COVID‐19 granulomatosis with polyangiitis |
| url | https://doi.org/10.1002/ccr3.8007 |
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