Excitatory neurons are more disinhibited than inhibitory neurons by chloride dysregulation in the spinal dorsal horn
Neuropathic pain is a debilitating condition caused by the abnormal processing of somatosensory input. Synaptic inhibition in the spinal dorsal horn plays a key role in that processing. Mechanical allodynia – the misperception of light touch as painful – occurs when inhibition is compromised. Disinh...
Main Authors: | Kwan Yeop Lee, Stéphanie Ratté, Steven A Prescott |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/49753 |
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