Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives
Abstract Post-translational methylation of histone lysine or arginine residues plays important roles in gene regulation and other physiological processes. Aberrant histone methylation caused by a gene mutation, translocation, or overexpression can often lead to initiation of a disease such as cancer...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2016-06-01
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| Series: | Journal of Hematology & Oncology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13045-016-0279-9 |