Identification of Insulin-Mimetic Plant Extracts: From an In Vitro High-Content Screen to Blood Glucose Reduction in Live Animals
Type 2 diabetes mellitus (T2DM) is linked to insulin resistance and a loss of insulin sensitivity, leading to millions of deaths worldwide each year. T2DM is caused by reduced uptake of glucose facilitated by glucose transporter 4 (GLUT4) in muscle and adipose tissue due to decreased intracellular t...
Main Authors: | Verena Stadlbauer, Cathrina Neuhauser, Tobias Aumiller, Alexander Stallinger, Marcus Iken, Julian Weghuber |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/14/4346 |
Similar Items
-
Fluorescence Microscopy-Based Quantitation of GLUT4 Translocation: High Throughput or High Content?
by: Verena Stadlbauer, et al.
Published: (2020-10-01) -
GLUT4 localisation with the plasma membrane is unaffected by an increase in plasma free fatty acid availability
by: J. S. Barrett, et al.
Published: (2024-04-01) -
Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake
by: Muheeb Beg, et al.
Published: (2017-06-01) -
Observing GLUT4 Translocation in Live L6 Cells Using Quantum Dots
by: Feng Qu, et al.
Published: (2011-02-01) -
ISOLATION AND PURIFICATION OF LYSOZYME FROM THE HEN EGG WHITE
by: S. S., et al.
Published: (2015-12-01)