MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma

MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma

Abstract Background MicroRNAs play crucial roles in tumorigenesis and tumor progression. miR-770 has been reported to be downregulated in several cancers and affects cancer cell proliferation, apoptosis, metastasis and drug resistance. However, the role and underlying molecular mechanism of miR-770...

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Bibliographic Details
Main Authors: Jun-feng Zhang, Jian-shui Zhang, Zhao-hua Zhao, Peng-bo Yang, Sheng-feng Ji, Nan Li, Qin-dong Shi, Jing Tan, Xi Xu, Cang-bao Xu, Ling-yu Zhao
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Cancer Cell International
Subjects:
miR-770
CDK8
Glioma
Proliferation
Cell cycle
Online Access:http://link.springer.com/article/10.1186/s12935-018-0694-9

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