Determination of residual virulence and immunogenicity of Mycobacterium bovis BCG-1 seed lots

Determination of residual virulence and immunogenicity of Mycobacterium bovis BCG-1 seed lots

The article is devoted to a challenging issue of stability of seed lot systems that have been used in Russia since 1947 to produce BCG vaccines. This problem is underexplored and needs further investigation. In an earlier study the authors of the article used innovative (molecular genetic) methods t...

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Bibliographic Details
Main Authors:	D. T. Levi, N. V. Aleksandrova, Yu. I. Obukhov
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2018-02-01
Series:	Биопрепараты: Профилактика, диагностика, лечение
Subjects:	вакцина бцж субштаммы бцж система посевных серий остаточная вирулентность приживаемость bcg vaccine bcg substrains seed lot system residual virulence survival
Online Access:	https://www.biopreparations.ru/jour/article/view/81

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