An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses.

Adeno-associated viruses (AAV) have evolved to exploit the dynamic reorganization of host cell machinery during co-infection by adenoviruses and other helper viruses. In the absence of helper viruses, host factors such as the proteasome and DNA damage response machinery have been shown to effectivel...

詳細記述

書誌詳細
主要な著者: Claire A Schreiber, Toshie Sakuma, Yoshihiro Izumiya, Sara J Holditch, Raymond D Hickey, Robert K Bressin, Upamanyu Basu, Kazunori Koide, Aravind Asokan, Yasuhiro Ikeda
フォーマット: 論文
言語:English
出版事項: Public Library of Science (PLoS) 2015-08-01
シリーズ:PLoS Pathogens
オンライン・アクセス:http://europepmc.org/articles/PMC4526370?pdf=render