A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid

The microwave-assisted three-component reactions of 3,5-bis(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones, acenaphthenequinone and cyclic α-amino acids in an ionic liquid, 1-butyl-3-methylimidazolium bromide, occurred through a domino sequence affording structurally intriguing diazaheptacyclic cag...

Full description

Bibliographic Details
Main Authors: Raju Suresh Kumar, Abdulrahman I. Almansour, Natarajan Arumugam, Mohammad Altaf, José Carlos Menéndez, Raju Ranjith Kumar, Hasnah Osman
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/2/165
_version_ 1819033762023866368
author Raju Suresh Kumar
Abdulrahman I. Almansour
Natarajan Arumugam
Mohammad Altaf
José Carlos Menéndez
Raju Ranjith Kumar
Hasnah Osman
author_facet Raju Suresh Kumar
Abdulrahman I. Almansour
Natarajan Arumugam
Mohammad Altaf
José Carlos Menéndez
Raju Ranjith Kumar
Hasnah Osman
author_sort Raju Suresh Kumar
collection DOAJ
description The microwave-assisted three-component reactions of 3,5-bis(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones, acenaphthenequinone and cyclic α-amino acids in an ionic liquid, 1-butyl-3-methylimidazolium bromide, occurred through a domino sequence affording structurally intriguing diazaheptacyclic cage-like compounds in excellent yields.
first_indexed 2024-12-21T07:22:59Z
format Article
id doaj.art-57864ef447b94edd9fba9f01f9fa76b7
institution Directory Open Access Journal
issn 1420-3049
language English
last_indexed 2024-12-21T07:22:59Z
publishDate 2016-01-01
publisher MDPI AG
record_format Article
series Molecules
spelling doaj.art-57864ef447b94edd9fba9f01f9fa76b72022-12-21T19:11:45ZengMDPI AGMolecules1420-30492016-01-0121216510.3390/molecules21020165molecules21020165A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic LiquidRaju Suresh Kumar0Abdulrahman I. Almansour1Natarajan Arumugam2Mohammad Altaf3José Carlos Menéndez4Raju Ranjith Kumar5Hasnah Osman6Department of Chemistry, College of Science, King Saud University P. O. Box 2455, Riyadh 11451, Saudi ArabiaDepartment of Chemistry, College of Science, King Saud University P. O. Box 2455, Riyadh 11451, Saudi ArabiaDepartment of Chemistry, College of Science, King Saud University P. O. Box 2455, Riyadh 11451, Saudi ArabiaCentral Laboratory, College of Science, King Saud University P. O. Box 2455, Riyadh 11451, Saudi ArabiaDepartamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad Complutense, Madrid 28040, SpainDepartment of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625 021, Tamil Nadu, IndiaSchool of Chemical Sciences, Universiti Sains Malaysia, Minden 11800, Penang, MalaysiaThe microwave-assisted three-component reactions of 3,5-bis(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones, acenaphthenequinone and cyclic α-amino acids in an ionic liquid, 1-butyl-3-methylimidazolium bromide, occurred through a domino sequence affording structurally intriguing diazaheptacyclic cage-like compounds in excellent yields.http://www.mdpi.com/1420-3049/21/2/165diazaheptacyclic cage compoundsmulticomponent reactionsionic liquidmicrowave-assisted synthesis
spellingShingle Raju Suresh Kumar
Abdulrahman I. Almansour
Natarajan Arumugam
Mohammad Altaf
José Carlos Menéndez
Raju Ranjith Kumar
Hasnah Osman
A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid
Molecules
diazaheptacyclic cage compounds
multicomponent reactions
ionic liquid
microwave-assisted synthesis
title A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid
title_full A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid
title_fullStr A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid
title_full_unstemmed A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid
title_short A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid
title_sort sustainable approach to the stereoselective synthesis of diazaheptacyclic cage systems based on a multicomponent strategy in an ionic liquid
topic diazaheptacyclic cage compounds
multicomponent reactions
ionic liquid
microwave-assisted synthesis
url http://www.mdpi.com/1420-3049/21/2/165
work_keys_str_mv AT rajusureshkumar asustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT abdulrahmanialmansour asustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT natarajanarumugam asustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT mohammadaltaf asustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT josecarlosmenendez asustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT rajuranjithkumar asustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT hasnahosman asustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT rajusureshkumar sustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT abdulrahmanialmansour sustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT natarajanarumugam sustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT mohammadaltaf sustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT josecarlosmenendez sustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT rajuranjithkumar sustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid
AT hasnahosman sustainableapproachtothestereoselectivesynthesisofdiazaheptacycliccagesystemsbasedonamulticomponentstrategyinanionicliquid