Heterohybridoma for the production of non murine monoclonal antibodies

Hybridoma technology described by kohler and Milstein produce only mouse immunoglobulins. Such immunoglobulins have limited use due to its negative side effects such as the recipient’s immune response. The production of a non murine monoclonal antibody to combat the problems of murine...

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Main Author: Kh.Victoria Chanu and M. Ayub Ali
Format: Article
Language:English
Published: Veterinary World 2010-01-01
Series:Veterinary World
Subjects:
Online Access:http://www.scopemed.org/mnstemps/2/2-1286562301.pdf
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author Kh.Victoria Chanu and M. Ayub Ali
author_facet Kh.Victoria Chanu and M. Ayub Ali
author_sort Kh.Victoria Chanu and M. Ayub Ali
collection DOAJ
description Hybridoma technology described by kohler and Milstein produce only mouse immunoglobulins. Such immunoglobulins have limited use due to its negative side effects such as the recipient’s immune response. The production of a non murine monoclonal antibody to combat the problems of murine monoclonal antibody is again difficult due to the lack of a suitable myeloma cell line. Heterohybridoma formed by the fusion of lymphocyte of one species with the myeloma cell of a different species is the solution, which can be used for the production of non murine monoclonal antibodies. [Veterinary World 2010; 3(8.000): 390-392]
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spelling doaj.art-57866aae1d4642b087c4af90bf8d8e0a2022-12-21T16:42:58ZengVeterinary WorldVeterinary World0972-89882010-01-0138.000390392Heterohybridoma for the production of non murine monoclonal antibodiesKh.Victoria Chanu and M. Ayub AliHybridoma technology described by kohler and Milstein produce only mouse immunoglobulins. Such immunoglobulins have limited use due to its negative side effects such as the recipient’s immune response. The production of a non murine monoclonal antibody to combat the problems of murine monoclonal antibody is again difficult due to the lack of a suitable myeloma cell line. Heterohybridoma formed by the fusion of lymphocyte of one species with the myeloma cell of a different species is the solution, which can be used for the production of non murine monoclonal antibodies. [Veterinary World 2010; 3(8.000): 390-392]http://www.scopemed.org/mnstemps/2/2-1286562301.pdfheterohybridomanon-murinelymphocytesmyeloma cellmonoclonal antibodies
spellingShingle Kh.Victoria Chanu and M. Ayub Ali
Heterohybridoma for the production of non murine monoclonal antibodies
Veterinary World
heterohybridoma
non-murine
lymphocytes
myeloma cell
monoclonal antibodies
title Heterohybridoma for the production of non murine monoclonal antibodies
title_full Heterohybridoma for the production of non murine monoclonal antibodies
title_fullStr Heterohybridoma for the production of non murine monoclonal antibodies
title_full_unstemmed Heterohybridoma for the production of non murine monoclonal antibodies
title_short Heterohybridoma for the production of non murine monoclonal antibodies
title_sort heterohybridoma for the production of non murine monoclonal antibodies
topic heterohybridoma
non-murine
lymphocytes
myeloma cell
monoclonal antibodies
url http://www.scopemed.org/mnstemps/2/2-1286562301.pdf
work_keys_str_mv AT khvictoriachanuandmayubali heterohybridomafortheproductionofnonmurinemonoclonalantibodies