Heterohybridoma for the production of non murine monoclonal antibodies
Hybridoma technology described by kohler and Milstein produce only mouse immunoglobulins. Such immunoglobulins have limited use due to its negative side effects such as the recipient’s immune response. The production of a non murine monoclonal antibody to combat the problems of murine...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Veterinary World
2010-01-01
|
Series: | Veterinary World |
Subjects: | |
Online Access: | http://www.scopemed.org/mnstemps/2/2-1286562301.pdf |
_version_ | 1819350192294461440 |
---|---|
author | Kh.Victoria Chanu and M. Ayub Ali |
author_facet | Kh.Victoria Chanu and M. Ayub Ali |
author_sort | Kh.Victoria Chanu and M. Ayub Ali |
collection | DOAJ |
description | Hybridoma technology described by kohler and Milstein produce only mouse immunoglobulins. Such immunoglobulins have limited use due to its negative side effects such as the recipient’s immune response. The production of a non murine monoclonal antibody to combat the problems of murine monoclonal antibody is again difficult due to the lack of a suitable myeloma cell line. Heterohybridoma formed by the fusion of lymphocyte of one species with the myeloma cell of a different species is the solution, which can be used for the production of non murine monoclonal antibodies. [Veterinary World 2010; 3(8.000): 390-392] |
first_indexed | 2024-12-24T19:12:30Z |
format | Article |
id | doaj.art-57866aae1d4642b087c4af90bf8d8e0a |
institution | Directory Open Access Journal |
issn | 0972-8988 |
language | English |
last_indexed | 2024-12-24T19:12:30Z |
publishDate | 2010-01-01 |
publisher | Veterinary World |
record_format | Article |
series | Veterinary World |
spelling | doaj.art-57866aae1d4642b087c4af90bf8d8e0a2022-12-21T16:42:58ZengVeterinary WorldVeterinary World0972-89882010-01-0138.000390392Heterohybridoma for the production of non murine monoclonal antibodiesKh.Victoria Chanu and M. Ayub AliHybridoma technology described by kohler and Milstein produce only mouse immunoglobulins. Such immunoglobulins have limited use due to its negative side effects such as the recipient’s immune response. The production of a non murine monoclonal antibody to combat the problems of murine monoclonal antibody is again difficult due to the lack of a suitable myeloma cell line. Heterohybridoma formed by the fusion of lymphocyte of one species with the myeloma cell of a different species is the solution, which can be used for the production of non murine monoclonal antibodies. [Veterinary World 2010; 3(8.000): 390-392]http://www.scopemed.org/mnstemps/2/2-1286562301.pdfheterohybridomanon-murinelymphocytesmyeloma cellmonoclonal antibodies |
spellingShingle | Kh.Victoria Chanu and M. Ayub Ali Heterohybridoma for the production of non murine monoclonal antibodies Veterinary World heterohybridoma non-murine lymphocytes myeloma cell monoclonal antibodies |
title | Heterohybridoma for the production of non murine monoclonal antibodies |
title_full | Heterohybridoma for the production of non murine monoclonal antibodies |
title_fullStr | Heterohybridoma for the production of non murine monoclonal antibodies |
title_full_unstemmed | Heterohybridoma for the production of non murine monoclonal antibodies |
title_short | Heterohybridoma for the production of non murine monoclonal antibodies |
title_sort | heterohybridoma for the production of non murine monoclonal antibodies |
topic | heterohybridoma non-murine lymphocytes myeloma cell monoclonal antibodies |
url | http://www.scopemed.org/mnstemps/2/2-1286562301.pdf |
work_keys_str_mv | AT khvictoriachanuandmayubali heterohybridomafortheproductionofnonmurinemonoclonalantibodies |